BACKGROUND The relationship between serum homocysteine levels and non-alcoholic fatty liver disease is poorly understood. This study aims to investigate the sex-specific relationship between serum homocysteine level and non-alcoholic fatty liver disease in the Korean population. METHODS This cross-sectional study included 150 men and 132 women who participated in medical examination programs ...

BACKGROUND We tested the hypothesis that observationally and genetically increased YKL-40 concentrations are associated with alcoholic liver and pancreas damage and disease. METHODS We performed cohort and mendelian randomization in 86,258 individuals from the Danish general population, with measured concentrations of plasma YKL-40 (n = 21 646) and CHI3L1 rs4950928 genotype (n = 84 738). RE...

INTRODUCTION Uganda is among the top ten consumers of alcohol worldwide though there is little data on alcohol related liver disease. We describe alcohol use, alcohol misuse, and alcoholic liver disease among adults at the emergency admission service of a large urban hospital in Uganda. METHODS All adults who consented were prospectively evaluated for alcohol use by inquiry and alcohol misuse...

common cancer and the third leading cause of cancer-related deaths. A known risk factor for HCC is non-alcoholic fatty liver disease (NAFLD), a continuum hepatic disorders related to obesity metabolic syndrome. AIM: We conducted an observational study identify factors hepatocellular in patients with who came SMHRC Nagpur routine visit. MATERIAL AND METHODS: The included 300 people aged 35 85 ye...

A large proportion of heavy drinkers develop serious alcoholic liver disease. Susceptibility to alcoholic hepatitis and cirrhosis appears to be influenced by heredity, gender, diet, and co-occurring liver illness. Most alcoholic liver damage is attributed to alcohol metabolism. Liver injury may be caused by direct toxicity of metabolic by-products of alcohol as well as by inflammation induced b...

Introduction N-terminal propeptide of procollagen type III (PIIINP) is generated during the synthesis of type III collagen. PIIINP can be measured in the serum as an indicator of liver fibrosis and cirrhosis. Aim To evaluate the effect of liver diseases of different aetiologies and clinical severity of liver cirrhosis on the serum level of PIIINP. Material and methods Patients with alcoholi...

BACKGROUND & AIMS Non-alcoholic fatty liver disease is a common cause of chronic liver disease. Celiac disease alters intestinal permeability and treatment with a gluten-free diet often causes weight gain, but so far there are few reports of non-alcoholic fatty liver disease in patients with celiac disease. METHODS Population-based cohort study. We compared the risk of non-alcoholic fatty liv...

BACKGROUND Alcoholic liver disease has a known aetiology but a complex and incompletely known pathogenesis. It is an extremely common disease with significant morbidity and mortality, but the reason why only a relatively small proportion of heavy drinkers progress to advanced disease remains elusive. AIM To recognize the factors responsible for the development and progression of alcoholic liv...