In previous studies, the relationship between aspartate aminotransferase to alanine aminotransferase ratio(AST/ALT ratio) and liver disease has been evaluated. In viral hepatitis, alcoholic liver disease and primary biliary cirrhosis, AST/ALT ratio has been proven to be an indicator of liver cirrhosis.1-3 AST/ALT ratio was a potential value in differentiating nonalcoholic steatohepatitis from a...

There are three phases of alcoholic liver disease: fatty liver, which is usually reversible with abstinence; alcoholic hepatitis, or liver inflammation; and cirrhosis, or scarring of the liver. Patients frequently have more than one type of liver disease, such as coexisting fatty liver and alcoholic hepatitis or alcoholic hepatitis together with cirrhosis. Patients with both cirrhosis and alcoh...

One of the most common public liver diseases over world is fatty which contain alcoholic and non-alcoholic liver. One-fourth among general population are impact Non-Alcoholic Fatty Liver Disease (NAFLD) in worldwide.Retinol binding protein 4 (RBP4) known as an adipokine, mainly synthesized secreted from form adipose tissues. RBP4 acts a transporter specifically bound to retinol others Visfatin ...

Although non-alcoholic fatty liver disease has been reported as a cardiometabolic risk factor, the effect of non-alcoholic fatty liver is yet to be clarified on abdominal obesity. Therefore, this study was conducted to investigate the longitudinal relationship of non-alcoholic fatty liver on the development of abdominal obesity. The study participants were composed of 11,212 Korean men without ...

Previous studies have reported inconsistent findings regarding the association between plasmatic higher of homocysteine level and non-alcoholic fatty liver disease. We aimed to investigate this association by conducting a meta-analysis. Literature was searched on PubMed from inception to January 2015. Eight studies evaluating plasma level of homocysteine in biopsy-proven non-alcoholic fatty liv...

Objectives: This study aimed to investigate the effects of non-alcoholic fatty liver disease on thyroid nodule prevalence
 Methods: A total 384 patients who were followed up with Grade 2-3 Non-Alcoholic Fatty Liver diagnosis investigated for presence multinodular and/or nodular goiter. Demographic characteristics, biochemical data, and abdominal ultrasonography reports collected from patie...

BACKGROUND Alcoholic liver disease has a known aetiology but a complex and incompletely known pathogenesis. It is an extremely common disease with significant morbidity and mortality, but the reason why only a relatively small proportion of heavy drinkers progress to advanced disease remains elusive. AIM To recognize the factors responsible for the development and progression of alcoholic liv...

Patients with chronic liver diseases are asymptomatic or have only vague non-specific symptoms. Effective medical treatments for chronic liver disease (before cirrhosis is established) are becoming increasingly available and since abnormal LFTs may be the only indication of this diseases. Aims: comparative study on serum Enzyme levels in various liver diseases. Discussion: serum Alkaline phosph...

BACKGROUND The relationship between serum homocysteine levels and non-alcoholic fatty liver disease is poorly understood. This study aims to investigate the sex-specific relationship between serum homocysteine level and non-alcoholic fatty liver disease in the Korean population. METHODS This cross-sectional study included 150 men and 132 women who participated in medical examination programs ...

BACKGROUND Alcoholic liver disease is associated with increased hepatic expression of monocyte chemoattractant protein 1 (MCP-1) and macrophage inflammatory protein 1alpha (MIP-1alpha). AIMS To determine whether concentrations of chemokines in the peripheral circulation reflect disease activity, and whether chemokine secretion is restricted to the liver or is part of a systemic inflammatory r...