BACKGROUND Rhizoma Pinelliae is the dried tuber of Pinellia ternata (Thunb.) Breit. Modern pharmacological studies have shown that Rhizoma Pinelliae has antitussive, antiemetic, glandular secretion inhibiting and antitumor effects. OBJECTIVES To optimize the processing technology of Rhizoma Pinelliae Praeparatum, and to study its anti-tumor effect. METHODS Orthogonal design method was appli...

Xiexin decoction, a herbal therapeutic agent commonly used in traditional Chinese medicine, is recognized for its beneficial effects on diabetic nephropathy exerted through the combined action of multiple components, including Rhizoma Coptidis alkaloids (A), Radix et Rhizoma Rhei polysaccharides (P), and Radix Scutellaria flavones (F). Our previous studies have shown that a combination of A, P,...

Background: The unique pharmaceutical methods for the processing of botanical drugs according to theory traditional Chinese medicine (TCM) affect clinical syndrome differentiation and treatment. objective this study was comprehensively elucidate principles mechanisms an herbal method by investigating alterations in metabolites Rhizoma Atractylodis Macrocephalae (AMR) processed Aurantii Fructus ...

Cimicifugae rhizoma (C. rhizoma) called Shengma (Chinese), Seungma (Korean), and Shoma (Japanese) is primarily derived from Cimicifuga heracleifolia Komarov or Cimicifuga foetida Linnaeus. C. rhizoma is used for anti-inflammatory, analgesic, antipyretic remedy and alternative for hormone replacement therapy. The aim of this study was to determine the dose-dependent anti-inflammatory and tumor s...

Coptidis Rhizoma (Coptis chinensis) has been reported to have antioxidative effect on hemolysis of erythrocytes induced by acetylphenylhydrazine in mice and rats. However, the ability of Coptidis Rhizoma to protect structure and function of erythrocytes membrane and morphology of erythrocytes against oxidative damage remains unknown. In this study, we undertook a characterization of antioxidati...

BACKGROUND/AIMS Reports have suggested that the traditional Chinese medicine Smilacis Glabrae Rhizoma attenuates hyperuricemia, but its mechanism is unclear. Our previous study demonstrated that uric acid could induce the generation of reactive oxygen species(ROS), which subsequently cause endothelial dysfunction. Therefore, we focused on the oxidative stress process. In this study, we would us...

BACKGROUND AND OBJECTIVES Astractylodes Rhizoma is commonly used in Korean folk medicine for digestion, diuresis, sedation, antibacterial agent. The present study was performed to explore the antioxidant capacities of methanolic extract of Astractylodes Rhizoma. In addition, its effect on the expression of inducible nitric oxide synthase (iNOS) in response to lipopolysaccharides (LPS) and osteo...

BACKGROUND Rhei Rhizoma has been widely used as a traditional herbal medicine to treat various inflammatory diseases. The present study was conducted to evaluate its anti-inflammatory activity against experimental reflux-induced esophagitis (RE) in SD rats. METHODS Rhei Rhizoma was administered at 125 or 250 mg/kg body weight per day for 7 days prior to the induction of reflux esophagitis, an...

BACKGROUND Atractylodis rhizoma is one of the most often used drugs in traditional Chinese medicine. Stir frying with wheat bran is the most common processing method. To clarify the principle of processing, an experiment was carried out to compare the tissue distribution of typical constituent after oral administration of raw A. rhizoma and processed ones. OBJECTIVE To compare the tissues dis...