Background: Rhinitis is a prevalent chronic inflammatory disease of the nasal mucosa. Arachidonic acid-derived lipoxin A4 (LXA4) has long been recognized to exert crucial anti-inflammatory and pro-resolving effects on inflammatory responses through a specific receptor named formyl peptide receptor-2 (FPR2). This study aimed to determine the serum level of LXA4 as well as the relative mRNA expre...

Background: Fungal aeroallergens might sensitize the airway which in turn produces a specific cytokine profile. Objective: To evaluate the IL-25 and IL-33 profile in patients with fungal allergic rhinitis. Methods: The present study examined patients who were evaluated due to allergic rhinitis (AR) at Emam Reza Hospital of Shiraz, Iran. The all...

specific local immunotherapy has been recently introduced as an alternative to classic subcutaneous immunotherapy in treatment of allergic rhinitis. in this study, the effects of sublingual immunotherapy (slit) on symptoms and medication score and skin prick test evaluation of patients with allergic rhinitis were investigated. in this placebo controlled trial, twenty four patients aged 5-18 yea...

introduction:the prevalence of atopic diseases has increased in recent decades dramatically. the most common aeroallergens in northeastern iran have not been fully defined. define the most common aeroallergens in allergic patients based on the skin prick test (spt) was aimed in this investigation.materials and methods:this cross-sectional study enrolled 1,006 allergic patients (aged 1–86 years)...

background: regulatory cd4+t (treg) cells are effective in maintaining immune tolerance. objective: to investigate single nucleotide polymorphisms (snps) of transforming growth factor β-1 (tgf-β1) and forkhead box protein 3 (foxp3) genes in iranian patients with allergic rhinitis (ar). methods: variations at codons 10 and 25 of tgf-β1 and foxp3 at positions -3279 a>c and -924 a>g were evaluated...

background: contact dermatitis (cd) is a significant problem among nurses. although there are reports about the prevalence of cd from different parts of the world, data about its frequency in turkey and about allergic contact sensitization among nurses is insufficient. objective: to define the frequency and patterns of allergic contact sensitization and related symptoms in practicing and studen...

introduction allergic rhinitis, like other allergic diseases, is one of the most common disorders during childhood; this study was conducted to assess and compare the prevalence and severity of allergic rhinitis in children and adolescents living in kurdistan province. the study was aimed to provide a ground for the identification of likely causes and risk factors of this disorder. materials an...

inhalation of fungal spores is shown to participate in the development of allergic rhinitis symptoms. in this study, relation between presence of alternaria in the human nasal cavity and allergic rhinitis is assessed. in a case-control study, 58 allergic rhinitis patients were compared with a well-matched control group of fifty healthy volunteers for sensitization to alternaria (by skin prick t...

allergic rhinitis is a chronic respiratory disease. sympathetic hypofunction is identified in all of the allergic rhinitis patients. moreover, allergic rhinitis is associated with decreased peak nasal inspiratory flow (pnif) and impaired lung functions. the aim of this study was to investigate effects of six-week of aquatic exercise on the autonomic nervous system function, pnif and lung functi...