Bronchopulmonary aspergillosis is usually caused by Aspergillus fumigatus. The six cases from the Sudan reported here were due to Aspergillus flavus. Three of the patients had primary invasive disease, one had Aspergillus mycetoma in a pre-existing lung cavity, and two had allergic aspergillosis. A special feature of the invasive disease was the clinical and radiographic simulation of malignanc...

The purposes of this study were to quanititate and correlate the findings of pathologic specimens and fungal culture in patients with a diagnosis of allergic fungal rhinosinusitis. Seventeen patients were identified between 2003 and 2005 with noninvasive fungal rhinosinusitis. Surgical specimens were analyzed via routine and special pathologic processing and compared to the microbiological resu...

Nonallergic rhinitis with eosinophilia syndrome (NARES) is a clinical syndrome comprising symptoms consistent with allergic rhinitis in which an absence of atopy has been demonstrated by allergen skin testing, and nasal cytology analysis demonstrates more than 20% eosinophils. Anosmia is a prominent feature not shared with allergic rhinitis. The pathophysiology of NARES is poorly understood, bu...

hyperspectral sensors provide a large number of spectral bands. this massive and complex data structure of hyperspectral images presents a challenge to traditional data processing techniques. therefore, reducing the dimensionality of hyperspectral images without losing important information is a very important issue for the remote sensing community. we propose to use overlap-based feature weigh...

Dubowitz syndrome is a rare, autosomal recessive disorder characterized by intrauterine growth retardation, short stature, microcephaly, distinct facial dysmorphism, and psychomotoric retardation. The hyper-immunoglobulin E (hyper-IgE or Job syndrome) is a primary immunodeficiency characterized by recurrent staphylococcal abscesses, recurrent cyst-forming pneumonia, and an elevated serum IgE le...

Nearly half of the world's population harbors helminth infections or suffers from allergic disorders. A common feature of this population is the so-called "type 2 immune response," which confers protection against helminths, but also promotes pathologic responses associated with allergic inflammation. However, the mechanisms that initiate and control type 2 responses remain enigmatic. Recent ad...

In asthma, airflow obstruction is thought to result primarily from inflammation-triggered airway smooth muscle (ASM) contraction. However, anti-inflammatory and smooth muscle-relaxing treatments are often temporary or ineffective. Overproduction of the mucin MUC5AC is an additional disease feature that, while strongly associated pathologically, is poorly understood functionally. Here we show th...

the prevalence of allergic disorders has increased markedly throughout the world over the past three decades. it seems probable that the increased prevalence is real because longitudinal studies have shown a rapid exponential increase in allergic disor¬ders. in order to determine the prevalence of type 1 allergy in patients with allergic disorders in sistan-blouchestan province, in the southeas...

the  frequency of  allergic diseases such  as allergic rhinitis is considerable in general population. insect aeroallergens are important allergens which can induce airway inflammation. the aim of this study was to determine the prevalence of sensitization to insect aeroallergens in allergic rhinitis patients in yazd as a desert city in iran. a cross-sectional study was undertaken on 95 allergi...

A new drug, AH 7725, with properties similar to those of disodium cromoglycate (Intal) has the additional feature of being effective when taken by mouth. Six patients with allergic asthma were studied by bronchial challenge tests with antigen. In every one the drug was found to inhibit (either partially or completely) the immediate-type asthmatic response. Late responses were not influenced. Th...