PURPOSE Allergic disease and its comorbidities significantly influence the quality of life. Although the comorbidities of allergic diseases are well described in adult populations, little is known about them in preschool children. In the present study, we aimed to assess the prevalence and comorbidity of allergic diseases in Korean preschool children. METHODS We conducted a cross-sectional st...

BACKGROUND Several studies demonstrated that placebo treatment may have a significant impact on many different symptoms. While in the traditional view concealment of the placebo is essential, recent studies report intriguing evidence that placebos may work even without deception. For example, it has been demonstrated that open-label placebos can improve symptoms in allergic rhinitis. However, t...

BACKGROUND For the development of forecasts for seasonal allergic rhinitis symptoms, it is essential to understand the relationship between grass pollen concentrations and the symptoms of grass pollen allergic patients. OBJECTIVE The aim of this study was to delineate this relationship between seasonal allergic rhinitis symptoms and grass pollen concentrations in the Netherlands. METHODS Gr...

The aim of this study was to contrast the prevalence of allergic symptoms in children living in urban and rural areas of Saudi Arabia and to investigate factors associated with any differences found. A cross-sectional questionnaire survey was conducted of a social class-stratified sample of 1,020 urban and 424 rural 12 yr old children, recording symptoms of current and past allergic disease and...

BACKGROUND We investigated the early efficacy of topical levocabastine, an H(1) histamine-receptor antagonist, in improving the clinical symptoms of allergic conjunctivitis. METHODS Thirty-six patients with allergic conjunctivitis were enrolled. One drop of levocabastine was instilled in one eye and one drop of artificial tears in the contralateral eye. Clinical examinations were performed be...

OBJECTIVES To report the incidence of allergic rhinitis in singers with nonspecific laryngeal examination findings and to correlate the incidence of allergic rhinitis with their vocal symptoms when present. DESIGN A retrospective review of all the medical records of singers with nonspecific laryngeal findings who presented to a specialty voice center for either vocal training or therapy betwe...

PURPOSE In Korea, tree pollens are known to be prevalent in spring, grass pollens in summer and weed pollens in autumn. However, few studies have revealed their seasonal specificity for allergic rhinitis symptoms. An ARIA (Allergic Rhinitis and its Impact on Asthma) classification of allergic rhinitis was recently introduced and its clinical validation has not been well proved. The aim of this ...

Epidemiological data suggests that the prevalence of allergic rhinitis is increasing worldwide [1]. Despite this, symptoms of allergic rhinitis are often underestimated by patients or are perceived as ‘normal’. Surveys of allergy sufferers across the United States of America have reported up to 61% of individuals being tolerant or able to ignore symptoms of allergic rhinitis, but over 80% of th...

BACKGROUND Proinflammatory mediators such as the cysteinyl leukotrienes are important in the pathophysiology of allergic rhinitis. This study evaluated the efficacy and tolerability of montelukast, a cysteinyl leukotriene receptor antagonist, given once daily in the morning for treatment of seasonal (fall) allergic rhinitis for 4 weeks. METHODS This was a randomized, double-blind trial with a...