The mechanism of imidazole-induced contraction on the bovine tracheal smooth muscle was investigated. Imidazole induced muscle contraction in a concentration-dependent manner on bovine, porcine and guinea-pig tracheas, but not in rat or mouse. In bovine tracheas, imidazole was cumulatively applied and induced muscle tension and increasesd intracellular Ca2+ level in a concentration -dependent m...

BACKGROUND Peak dP/dt is a good index of ventricular performance that is not influenced by afterload, wall motion abnormalities, or the variations in ventricular anatomy and morphology commonly encountered among patients with congenital heart disease. Unfortunately, the clinical utility of peak dP/dt has been limited by the fact that its measurement generally requires an intraventricular cathet...

in this paper we define a new type of rings ”almost powerhermitian rings” (a generalization of almost hermitian rings) and establish several sufficient conditions over a ring r such that, every regular matrix admits a diagonal power-reduction.

Cholecystokinin-octapeptide (CCK-OP) evoked contraction and 3H-acetylcholine (3H-ACh) release of the muscle strip of the guinea pig gallbladder were studied. Although hexamethonium (10(-5) M) or tetrodotoxin (10(-6) M) had no effect on CCK-OP (10(-8) M) evoked contraction and 3H-ACh release, Ca-free medium almost completely abolished CCK-OP (10(-8) M) evoked 3H-ACh release. In Ca-free medium co...

in this paper we discuss on the fixed points of asymptotic contractions and boyd-wong type contractions in uniform spaces equipped with an e-distance. a new version ofkirk's fixed point theorem is given for asymptotic contractions and boyd-wong type contractions is investigated in uniform spaces.

Objective(s): Recently, we showed that some new synthetic compounds structurally related to cilostamide (4-(1,2-dihydro-2-oxoquinolin-6-hydroxy)- N-cyclohexyl-N-methylbutanamide), a selective phosphodiesterase 3 (PDE3) inhibitor, produce inotropic effect comparable to that of IBMX (3-isobutyl-1-methylxanthine), a non-selective PDE inhibitor, but with differential chronotropic effect. In this in...

in this paper, we establish and prove the existence of best proximity points for multivalued cyclic $f$- contraction mappings in complete metric spaces. our results improve and extend various results in literature.

recently, choudhury and metiya [fixed points of weak contractions in cone metric spaces, nonlinear analysis 72 (2010) 1589-1593] proved some fixed point theorems for weak contractions in cone metric spaces. weak contractions are generalizations of the banach's contraction mapping, which have been studied by several authors. in this paper, we introduce the notion of $f$-weak contractions and als...