This study was designed to demonstrate the cytoprotective effect of an antacid containing aluminium phosphate (Phosphalugel) against ethanol-induced gastric injury in the rat and to determine whether this cytoprotective effect is mediated by endogenous prostaglandins and sulfhydryls. We have quantitatively evaluated gastric mucosal lesions using macroscopic and histological techniques one hour ...

Calcium phosphate based biomaterials are extensively used in the context of tissue engineering: small changes in composition can lead to significant changes in properties allowing their use in a wide range of applications. Samples of composition (Al(2)O(3))(x)(Na(2)O)(0.11-x)(CaO)(0.445)(P(2)O(5))(0.445), where x = 0, 0.03, 0.05, and 0.08, were prepared by melt quenching. The atomic-scale struc...

It is well known that aluminium is potentially neurotoxic. Moreover, there has been concern in recent years that dietary and environmental exposure to aluminium might cause developmental toxicity in mammals. While it is well established that aluminium may be a developmental toxic when administered parenterally, until recently there was little concern about embryo/fetal consequences of aluminium...

Aluminium salt slag (also known as aluminium salt cake), which is produced by the secondary aluminium industry, is formed during aluminium scrap/dross melting and contains 15-30% aluminium oxide, 30-55% sodium chloride, 15-30% potassium chloride, 5-7% metallic aluminium and impurities (carbides, nitrides, sulphides and phosphides). Depending on the raw mix the amount of salt slag produced per t...

AIMS To determine a possible mechanism to explain the presence of aluminium lines within fully calcified bone in aluminium-related osteomalacia. METHODS Fifty five bone cases shown by bone biopsy to be aluminium-related osteomalacia were studied. In 38 specimens aluminium lines were identified within calcified bone by means of the Aluminon stain and a characteristic form of patchy mineralisat...

The gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in vertebrate CNS. At GABAergic synapses, a high-affinity transporter exists, which is responsible for GABA reuptake and release during neurotransmission. GABA transporter activity depends on the phosphorylation/dephosphorylation state, being modulated by Ca(2+)/calmodulin-dependent protein phosphatase 2B (calcineurin)....

Aluminium adjuvants remain the most widely used and effective adjuvants in vaccination and immunotherapy. Herein, the particle size distribution (PSD) of aluminium oxyhydroxide and aluminium hydroxyphosphate adjuvants was elucidated in attempt to correlate these properties with the biological responses observed post vaccination. Heightened solubility and potentially the generation of Al(3+) in ...

It is well known that aluminium is today the most widely used metallic material besides steel. The mechanical characteristics of aluminium offer an increasing application field, especially where lightweight constructions are required. The demands for improved characteristics such as higher strength and greater durability are achieved by the development of new aluminium alloys. Continuous effort...

Aluminium toxicity in acid soils having pH below 5.5, affects the production of staple food crops, vegetables and cash crops worldwide. About 50% of the world’s potentially arable lands are acidic. It is trivalent cationic form i.e. Al that limits the plant’s growth. Absorbed Aluminium inhibits root elongation and adversely affects plant growth. Recently researches have been conducted to unders...

The corrosion behaviour of aluminium and6063 aluminium alloy was investigated in phosphoric acid of different concentrations at different temperatures. The study was done by electrochemical method, using Tafel polarization and electrochemical impedance spectroscopy (EIS) techniques. The kinetic parameters and thermodynamic parameters were calculated using Arrhenius theory and transition state t...