نتایج جستجو برای: alzheimer disease ad

تعداد نتایج: 1556084  

Journal: :Applied and environmental microbiology 1993
A J van den Wijngaard R D Wind D B Janssen

With the pure bacterial cultures Ancylobacter aquaticus AD20 and AD25, Xanthobacter autotrophicus GJ10, and Pseudomonas sp. strain AD1, Monod kinetics was observed during growth in chemostat cultures on 1,2-dichloroethane (AD20, AD25, and GJ10), 2-chloroethanol (AD20 and GJ10), and 1,3-dichloro-2-propanol (AD1). Both the Michaelis-Menten constants (K(m)) of the first catabolic (dehalogenating) ...

Saman Esmaeilnejad, Sepideh Mansoori Majoofardi, Zahra Behrooznia,

Alzheimer disease (AD) is a progressive neurodegenerative brain disorder which plays an important role in neural cell destruction and as a result it causes memory loss in the patients. This disease is also the most common type of dementia which doesn’t completely respond to medical treatments so no certain cure is available. Recent studies show the advantages of using stem cells (SCs) in ...

Journal: :Clinical and Translational Imaging 2021

Several radiotracers have been employed to bind amyloid plaques in the brain for differential diagnosis of neurodegenerative disease, open possibility measure vivo pathogenic processes implicated Alzheimer disease (AD) and potential detect at earliest stages with a role clinical trials’ longitudinal assessment. Visual reading is clinically adequate clearly positive or negative cases but adoptio...

2013
Rowayda A. Sadek

Regional Atrophy analysis of structural magnetic resonance image (MRI) of the brain may provide quantitative evidence of different neurodegenerative diseases. This paper proposes an approach for early detection of Alzheimer disease (AD) by locating the atrophy in the brain. The paper proposes an automated computer aided system to for differential diagnosis of different neurodegenerative disease...

Journal: :مجله علوم اعصاب شفای خاتم 0
amir mahmoud ahmadzade student research committee, faculty of medicine, mashhad university of medical sciences, mashhad, iran farzin naseri student research committee, faculty of medicine, mashhad university of medical sciences, mashhad, iran sajad sahab negah a. department of neuroscience, mashhad university of medical sciences, mashhad, iran b. shefa neuroscience research center, khatam alanbia hospital, tehran, iran

one of the most serious neurodegenerative disorders is alzheimer disease (ad). as the population is aging and due to the fact that ad is more common in aged people, more attention must be paid to this disease. one of the main characteristics of ad is dementia which starts with loss of short term memory, then progresses and causes various brain dysfunctions such as loss of long term memory. inte...

Maryam MoghadamQaeini, Zahra SheidaeMehne,

Alzheimer’s disease (AD) is a neurodegenerative disorder and the most common form of dementia. Almost 47 million people suffer from dementia worldwide. AD accounts for approximately 60%–80% of all dementia cases. Three major pathologies characterize the disease: senile plaques, neurofibrillary tangles and inflammation. We review the literature on events contributing to the inflammat...

2016
Ronald L. Walton Alexandra I. Soto-Ortolaza Melissa E. Murray Oswaldo Lorenzo-Betancor Kotaro Ogaki Michael G. Heckman Sruti Rayaprolu Rosa Rademakers Nilüfer Ertekin-Taner Ryan J. Uitti Jay A. van Gerpen Zbigniew K. Wszolek Glenn E. Smith Kejal Kantarci Val J. Lowe Joseph E. Parisi David T. Jones Rodolfo Savica Jonathan Graff-Radford David S. Knopman Ronald C. Petersen Neill R. Graff-Radford Tanis J. Ferman Dennis W. Dickson Bradley F. Boeve Owen A. Ross Catherine Labbé

Dementia with Lewy bodies (DLB) is the second leading cause of neurodegenerative dementia in the elderly and is clinically characterized by the presence of cognitive decline, parkinsonism, REM sleep behavior disorder, and visual hallucinations.(1,2) At autopsy, α-synuclein-positive Lewy-related pathology is observed throughout the brain. Concomitant Alzheimer disease-related pathology including...

Journal: :Neurology 2004
S D Moffat A B Zonderman E J Metter C Kawas M R Blackman S M Harman S M Resnick

OBJECTIVE To investigate the relationships between age-associated decreases in endogenous serum total testosterone (T) and a free T index (FTI) in men and the subsequent development of Alzheimer disease (AD). METHOD The authors used a prospective, longitudinal design with follow-up in men since 1958. Participants were from the Baltimore Longitudinal Study of Aging, a community-dwelling volunt...

Journal: :Neurology 2008
D K Johnson M Storandt J C Morris Z D Langford J E Galvin

OBJECTIVE To re-examine proposed models of cognitive test performance that concluded separate factor structures were required for people with Alzheimer disease (AD) and older adults without dementia. METHODS Five models of cognitive test performance were compared using multistep confirmatory factor analysis in 115 individuals with autopsy-confirmed AD and 191 research participants without cli...

2012
Nabil Belmokhtar Nacéra Benamrane G. Auzias S. Lehéricy M-O. Habert M. Chupin H. Benali O. Colliot E. Ceyhan C. Ceritoglu M. F. Beg L. Wang J. C. Morris J. G. Csernansky M. I. Miller J. T. Ratnanather O. Querbes F. Aubry J. Pariente J. A. Lotterie J. F. Demonet V. Duret M. Puel I. Berry J. C. Fort Allen R. Dobbs A. Savio M. García-Sebastián C. Hernández M. Graña

With nearly 100. 000 cases in Algeria, Alzheimer's disease (AD) represents a major public health problem. Therefore, several different automated methods have been developed to assist clinicians in their diagnosis. We propose here a method based on binary support vector machines (SVM) to distinguish between patients with Alzheimer disease (AD), patients with mild cognitive impairment (MCI) ...

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