In yeast, most amino acid biosynthetic pathways are coregulated: starvation for a single amino acid results in derepression of enzyme activities for many different biosynthetic pathways. This phenomenon is referred to as "general control of amino acid biosynthesis." In this paper we describe the isolation and characterization of 43 amino acid analog-sensitive (aas-) mutants that are perturbed i...

In the last two decades, numerous oligopeptides have been isolated from sporogenic bacteria and fungi. These peptides are almost invariably characterized by the presence of macrocyclic structures, linkages other than cr-peptide bonds, amino acids that do not occur in protein, n-amino acids, and nonamino acid moieties. The formation of some of these peptides by microorganisms has been studied in...

In the last two decades, numerous oligopeptides have been isolated from sporogenic bacteria and fungi. These peptides are almost invariably characterized by the presence of macrocyclic structures, linkages other than cr-peptide bonds, amino acids that do not occur in protein, n-amino acids, and nonamino acid moieties. The formation of some of these peptides by microorganisms has been studied in...

an experiment was conducted to reevaluate the digestible lysine requirement of arian male broilers by comparing the performance of chicks fed different levels of cottonseed meal (csm) on a total amino acid (aa) versus a digestible aa basis. four hundred and thirty two (432) arian male broiler chicks were allotted to 18 treatments with four repli-cates of six chicks each in a completely randomiz...

Computational comparative techniques were applied to analysis of the aromatic amino acid regulon in Gram-positive bacteria. A new candidate transcription regulation signal of 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase and shikimate kinase genes was identified in Streptococcus and Lactococcus species. New T-boxes were found upstream of aromatic amino acid biosynthesis and transport gen...