OBJECTIVE To determine the postprocedure loss rate for mid-trimester genetic amniocentesis. OUTCOME Reduction of benign biopsy rates. BENEFITS To provide better advice for women about the risks and benefits of mid-trimester genetic amniocentesis, and to ensure that women are given sufficient information/counselling to make a decision about screening. SUMMARY STATEMENT The risk of postproc...

Since 1990 avoidance of methylene blue as a dye in diagnostic amniocentesis is recommended. This is a result of the observation that a high incidence of jejunoileal atresia appeared in twin pregnancies following intraamniotic injection of methylene blue. We report four further cases of jejunoileal atresia in twins after intraamniotic injection of dyes since 1991. We describe the clinical course...

with significant improve in health-care and treatment of infectious diseases, genetic disorders have created a new era of notification. changes in social attitude towards family life and tendency of parents for limited number of children, sense of responsibility of parents for mental and physical healthiness of children along with their education, needed a new strategy. since most genetic disor...

There have been many diagnostic techniques using amniotic fluid or placental villi, for which needed puncture of amniotic fluid (amniocentesis) and placental villi sampling (CVS) in early pregnancy. The techniques accompany some risk factors of fetal demise or miscarriage. Also immature fetal lung was diagnosed in preterm births by the chemical or physical property of amniotic fluid obtained by...

Microbiological analysis of amniotic fluid obtained by amniocentesis is increasingly employed in preterm premature rupture of the membranes (PPROM) to predict those patients at increased risk of chorioamnionitis. Although liquor culture appears the most accurate predictor, a role exists for rapid but slightly less accurate testing. In this study, a dipstick (Cytur-test) which predicts the prese...

Background: Prenatal diagnosis for Fetal Chromosomal anomalies currently relies on assessment of risk followed by a combination of biochemical and nuchal translucency. Trisomy 21 is the most common trisomy that is associated with intellectual disability. Pregnant women who receive a prenatal diagnosis of trisomy 21 currently have the option of continuing or terminating their pregnancy, but no f...

Sex chromatin studies were carried out on small amounts of amniotic fluid obtained by amniocentesis or from intact amniotic sacs removed at hysterotomy. Provided that satisfactory preparations were obtained the accuracy of fetal sexing was 87%. Nevertheless, in the management of a pregnancy in which there is a risk of a serious X-linked recessive disorder, repeat amniocentesis may be necessary ...