Fibrin clots have been detected at sites of inflammation, and kinins have been implicated as mediators of the vascular phenomena of acute inflammation, systemic shock, and disseminated intravascular coagulation. It is now reported that both negatively and positively charged asbestos fibers shorten the partial thromboplastin time of human plasma, indicating coagulation of the plasma. A sample co...

The aim of this study was to investigate the concentrations of airborne asbestos that can be released into classrooms of schools that have amosite-containing asbestos insulation board (AIB) in the ceiling plenum or other spaces, particularly where there is forced recirculation of air as part of a warm air heating system. Air samples were collected in three or more classrooms at each of three sc...

Details are given of the techniques used in the analysis of asbestiform fibers in the water systems of Duluth, Minnesota and other cities. Photographic electron diffraction and electron microprobe analyses indicated that the concentration of verified amphibole mineral fibers ranged from 20 x 10(6) to 75 x 10(6) fibers/l. Approximately 50-60% of the fibers were in the cummingtonite-grunerite ser...

Today, despite considerable efforts undertaken by the scientific community, mechanisms of carcinogenesis mineral fibres remain poorly understood. A crucial role in disclosing action is played vitro and vivo models. Such models require experimental design based on negative positive controls. Commonly used controls are amosite crocidolite UICC standards, while have not been identified so far. The...

Although theoretical models and experiments on animals exist that predict the distribution of asbestos fibres in the lung, there are few studies in man that relate to this question and they have generated contradictory results. To examine this distribution analytical electron microscopy was employed to determine the amosite fibre concentration, size, surface area, and mass in 29 circumferential...