Abstract. Variations in precipitation and atmospheric N deposition affect water availability desert thus may have significant effects on ecosystems. Haloxylon ammodendron is a dominant plant Asian desert, addressing its physiological acclimatization to the changes can provide insight into how plants adapt extreme environments by adjustment. Carbon isotope ratio (?13C) has been suggested as sens...

Abstract. Variations in precipitation and atmospheric N deposition affect water availability desert thus may have significant effects on ecosystems. Haloxylon ammodendron is a dominant plant Asian desert, addressing its physiological acclimatization to the changes can provide insight into how plants adapt extreme environments by adjustment. Carbon isotope ratio (δ13C) has been suggested as sens...

aims: job rotation is considered as one of the human resource development methods. this study was carried out to investigate the correlation between job rotation and visiting number of environmental health employees. materials & methods: this descriptive cross-sectional study was done on environmental health employees in three health centers of north, north west and east of tehran in 2011. 42 p...

abstract: knee joint has major role in lower extremity activities. emong different elements of knee joint complex, anterior cruciate ligament has becom more interested because of its alignment, structural complication, varied never receptors and frequently susceptibility to injury. afterinjury of this ligament knee extensor torque decreases. the aim of this research was that reduce of quadricep...

UNLABELLED Nucleotide signaling molecules are important intracellular messengers that regulate a wide range of biological functions. The human pathogen Staphylococcus aureus produces the signaling nucleotide cyclic di-AMP (c-di-AMP). This molecule is common among Gram-positive bacteria and in many organisms is essential for survival under standard laboratory growth conditions. In this study, we...

Ampelopsin (AMP), a plant flavonoid, has been reported to inhibit cell growth and/or induce apoptosis in various types of tumor. The aim of the present study was to assess the apoptosis-inducing activity of AMP in A549 human lung adenocarcinoma epithelial cells and the associated underlying mechanism. A549 cells were incubated with different concentrations of AMP in culture medium. Cell growth ...

Cyclic di-adenosine monophosphate (c-di-AMP) is a recently discovered signaling molecule important for the survival of Firmicutes, a large bacterial group that includes notable pathogens such as Staphylococcus aureus However, the exact role of this molecule has not been identified. dacA, the S. aureus gene encoding the diadenylate cyclase enzyme required for c-di-AMP production, cannot be delet...

The cyclic di-nucleotide bis-(3',5')-cyclic dimeric adenosine monophosphate (c-di-AMP) is a candidate mucosal adjuvant with proven efficacy in preclinical models. It was shown to promote specific humoral and cellular immune responses following mucosal administration. To date, there is only fragmentary knowledge on the cellular and molecular mode of action of c-di-AMP. Here, we report on the ide...

Listeria monocytogenes infection leads to robust induction of an innate immune signaling pathway referred to as the cytosolic surveillance pathway (CSP), characterized by expression of beta interferon (IFN-β) and coregulated genes. We previously identified the IFN-β stimulatory ligand as secreted cyclic di-AMP. Synthesis of c-di-AMP in L. monocytogenes is catalyzed by the diadenylate cyclase Da...