Using Microgenics unique technology, cloned enzyme donor immunoassay (CEDIA), the multiplex assay (CEDIA Amphetamines/Ecstasy) has been developed for the detection of amphetamine, methamphetamine, and ecstasy drugs at cutoff level either of 500 ng/mL or 1000 ng/mL applicable for either qualitative screening or semiquantitative measurement. The multiplex assay detects the total concentration of ...

s related to the Thesis  Armbruszt S., Abraham H., Figler M., Hajnal A. (2013) Életkortól függő változások a CART (cocaineand amphetamine regulated transcript) peptid immunreaktivitásában a táplálkozás-szabályozásért felelős agyi központok területén. PTE Egészségtudományi Doktori Iskola III. Tudományos Fóruma, Pécs.  Armbruszt S., Abraham H., Figler M., Hajnal A. (2013) A cocaineand amphetami...

BACKGROUND Numerous studies have indicated that serotonin (5-HT)1B receptor ligands affect the behavioral effects of psychostimulants (cocaine, amphetamine), including the reinforcing activities of these drugs. METHODS To substantiate a role for those receptors in incentive motivation for amphetamine, we used the extinction/reinstatement model to examine the effects of the 5-HT1B receptor lig...

background: a good proportion of poisoned patients treated at poisoning wards are elderly. this study was designed to evaluate the epidemiologic pattern of acute poisoning in elderly in hamadan, western iran. methods: in this retrospective cross-sectional study, poisoned patients aged 60 years and older treated at department of poisoning of farshchian hospital from march 2008 to march 2013 were...

background due to the chronic and recurrent nature of addiction, many people who quit drug addiction may slip back into the pattern of using drugs shortly after the detoxification period. emotion-regulation strategies and resilience play an important role in preventing the recurrences of substance abuse. objectives this study aimed to compare the effects of methadone-maintenance therapy (mmt) a...

conclusions the length of sensory and motor blockade is shorter in chronic opioid abusers. adding 10 µg sufentanil to hyperbaric bupivacaine in opium abusers lengthened the sensory and motor block duration. results the duration of sensory and motor block were significantly less in group c (537.0 ± 40.1 minutes, 479.0 ± 34.8 minutes) and the longest duration of sensory and motor block was observ...

background according to recent theories on addiction, attentional bias towards drug-related stimuli plays a pivotal role in the initiation of drug abuse. objectives the present study attempted to investigate attentional bias towards drug-related words in addicts and non-addicts. patients and methods to attain the objectives, following a causal-comparative study, a number of 15 addicts under tre...

OBJECTIVE Basic studies have demonstrated that optimal levels of prefrontal cortical dopamine are critical to various executive functions such as working memory, attention, inhibitory control, and risk/reward decisions, all of which are impaired in addictive disorders such as alcoholism. Based on this and imaging studies of alcoholism that have demonstrated less dopamine in the striatum, the au...

Hypertension is the commonest cause of intracerebral hemorrhage (ICH) but non-hypertensive intracerebral hemorrhages (NHICH) are not rare. We report three interesting cases of NHICH subsequent to amyloid angiopathy, alcoholic hepatitis and amphetamine abuse. They suggest the importance of recognizing these conditions and need for urgent specific therapy which may play a vital role in therapeuti...