نتایج جستجو برای: amprenavir

تعداد نتایج: 874  

Journal: :Physical review letters 2013
D Androic D S Armstrong A Asaturyan T Averett J Balewski J Beaufait R S Beminiwattha J Benesch F Benmokhtar J Birchall R D Carlini G D Cates J C Cornejo S Covrig M M Dalton C A Davis W Deconinck J Diefenbach J F Dowd J A Dunne D Dutta W S Duvall M Elaasar W R Falk J M Finn T Forest D Gaskell M T W Gericke J Grames V M Gray K Grimm F Guo J R Hoskins K Johnston D Jones M Jones R Jones M Kargiantoulakis P M King E Korkmaz S Kowalski J Leacock J Leckey A R Lee J H Lee L Lee S MacEwan D Mack J A Magee R Mahurin J Mammei J W Martin M J McHugh D Meekins J Mei R Michaels A Micherdzinska A Mkrtchyan H Mkrtchyan N Morgan K E Myers A Narayan L Z Ndukum V Nelyubin Nuruzzaman W T H van Oers A K Opper S A Page J Pan K D Paschke S K Phillips M L Pitt M Poelker J F Rajotte W D Ramsay J Roche B Sawatzky T Seva M H Shabestari R Silwal N Simicevic G R Smith P Solvignon D T Spayde A Subedi R Subedi R Suleiman V Tadevosyan W A Tobias V Tvaskis B Waidyawansa P Wang S P Wells S A Wood S Yang R D Young S Zhamkochyan

The Q(weak) experiment has measured the parity-violating asymmetry in ep elastic scattering at Q(2)=0.025(GeV/c)(2), employing 145 μA of 89% longitudinally polarized electrons on a 34.4 cm long liquid hydrogen target at Jefferson Lab. The results of the experiment's commissioning run, constituting approximately 4% of the data collected in the experiment, are reported here. From these initial re...

Journal: :Revista Brasileira de Ginecologia e Obstetrícia 2004

2009
Quang Vuong

We consider the structural estimation of the affiliated private value (APV) model in first.:p~ice sealed-bid auctions. The model allows for bidders' individual efficiencies and opportunity costs, while permitting dependence among bidders' private values through affiliation. We establish the non parametric identification ofthe APVmodel, characterize its theoretical restrictions, and pro­ pose a ...

2017
T Padmini L Satyanarayana

A validate rapid, economical and sensitive visible spectrophotometric method has been developed for quantitative determination of amprenavir in bulk drug and formulation samples. This method is validated for irinotecan with chromogenic reagent 3-methyl benzothiazolinone hydrazine (MBTH). The calibration curve was linear over Beer’s concentration range of 25-350 μg/ml. The relative standard devi...

2010
C Orkin E DeJesus H Khanlou A Stoehr K Supparatpinyo T Van de Casteele E Lathouwers S Spinosa-Guzman

Results 689 patients (30% female; mean BL VL 4.85 log10 cpm; median CD4 225 cells/mm) were randomised. Overall, significantly more DRV/r than LPV/r patients had VL <50 cpm at Wk 192, confirming DRV/r qd non-inferiority (p<0.001) and superiority (p=0.002) (Table 1). In patients with virological failure (VF; TLOVR non-VF censored) no developing primary PI mutations were identified in either arm; ...

Journal: :The Journal of infectious diseases 2007
Yumi Mitsuya Tommy F Liu Soo-Yon Rhee W Jeffrey Fessel Robert W Shafer

Eleven protease mutations have been associated with reduced susceptibility to darunavir (DRV). We examined the prevalence and covariates of these mutations in 2 populations. Thirty percent of 1175 Northern California patients and 24% of 2744 non-California patients in the Stanford HIV Drug Resistance Database had viruses with 1 or more mutations associated with resistance to DRV. In multivariat...

Journal: :Drug metabolism and disposition: the biological fate of chemicals 2008
Zhi-Wei Ye Patrick Augustijns Pieter Annaert

The present study was aimed at characterizing the in vitro cellular uptake mechanism and kinetics of the bile salt analog cholylglycylamido-fluorescein (CGamF) in sandwich-cultured rat hepatocytes (SCRHs). Concentration-dependent inhibition of active CGamF accumulation by seven human immunodeficiency virus (HIV) protease inhibitors (PIs) was also determined and compared with inhibition data obt...

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