The human equilibrative nucleoside transporter 1 (hENT1) is the major means by which gemcitabine enters human cells; recent evidence exists that hENT1 is expressed in carcinoma of the ampulla of Vater and that it should be considered as a molecular prognostic marker for patients with resected ampullary cancer. Aim of the present study is to evaluate the variations of hENT1 expression in ampulla...

Objectives: To contribute 3 additional cases of congenital ampullary atresia to the 5 in our previously published case series. To document the constant coexistence of ipsilateral fimbrial tissue, to review the literature and to reconcile this finding with novel concepts of ovarian carcinogenesis. Design: Case series. Setting: Tertiary academic referral centre. Patients: Cases of congenital ampu...

Ampullary organ electroreceptors excited by weak cathodal electric fields are used for hunting by both cartilaginous and non-teleost bony fishes. Despite similarities of neurophysiology and innervation, their embryonic origins remain controversial: bony fish ampullary organs are derived from lateral line placodes, whereas a neural crest origin has been proposed for cartilaginous fish electrorec...

BACKGROUND Adenocarcinomas of the ampulla of Vater are classified as biliary cancers, though the exact epithelium of origin for these cancers is not known. We sought to molecularly classify ampullary adenocarcinomas in comparison to known adenocarcinomas of the pancreas, bile duct, and duodenum by gene expression analysis. METHODS We analyzed 32 fresh-frozen resected, untreated periampullary ...

We report herein a case of a synchronous presentation of an adenocarcinoma of esophagago-gastric junction type II and an ampullary tumor that was treated by combined Whipple's pancreaticoduodenectomy, total gastrectomy and esophagectomy. The magnitude of this operation was safely achieved with meticulous surgical techniques and perioperative care without any major short or long term complicatio...

OBJECTIVE The aim of this project was to study the imaging characteristics of multi-detector CT (MDCT) in different types of malignant tumor in the common bile duct ampulla. PATIENTS AND METHODS We examined 30 cases of pancreatic head cancer, 35 of terminal cholangiocarcinoma, 26 of ampullary carcinoma, and 40 of benign lesions, all confirmed by pathology. We used 64-slice spiral CT plain sca...

BACKGROUND Pancreatic cancer (PC) has the worst survival of all periampullary cancers. This may relate to histopathological differences between pancreatic cancers and other periampullary cancers. Our aim was to examine the distribution and histopathologic features of pancreatic, ampullary, biliary and duodenal cancers resected with a pancreaticoduodenectomy (PD) and to examine local trends of p...

In electricfish ofthe mormyridfamily, an efference copy is present in the brain region that receives afferent input from ampullary electroreceptors. The efference copy is elicited by the motor command tofire the electric organ. Its effect is always opposite that of ampullary afferents responding to the electric organ discharge, and it changes to match variations in this afferent input. It proba...

In electric fish of the mormyrid family, an efference copy is present in the brain region that receives afferent input from ampullary electroreceptors. The efference copy is elicited by the motor command to fire the electric organ. Its effect is always opposite that the ampullary afferents responding to the electric organ discharge, and it changes to match variations in this afferent input. It ...