ferula gummosa boiss is a good source of biologically active compounds such as monoterpene and sesquiterpene derivatives. there are also several reports on antioxidant effects of these compounds. the aim of this study was to investigate the effect of daily administration of f. gummosa root hydro-alcoholic extract on serum oxidant-antioxidant status. twenty four wistar rats were randomly divided...

Injection of 3-amino-1,2,4-triazole into rats resulted in a rapid fall of liver catalase activity which gradually returned to the normal level, but the amount of catalase protein determined by the immunochemical method remained constant without any decrease in parallel with the enzyme activity. Inactivation occurred more rapidly with soluble catalase (or Catalase-II) than with catalase in perox...

Background and objectives: Hesperetin flavanone is a natural bioflavonoid found abundantly in citrus fruits with antioxidant and anti-inflammatory properties. Nano sizing techniques improve the bioavailability of poorly soluble drugs such as hesperetin. Main feature of Parkinson's disease is the degeneration of dopaminergic neurons in the substantia nigra. The rate of oxidative...

One of the earliest reports on the systemic effects of tumors was made by Brahn (2), who found that the liver catalase activity of human beings with cancer of the rectum, stomach, pancreas, and intestine was very much lower than normal. This systemic phenomenon later was studied extensively by Greenstein et al. (4-8) with the use of a large number and variety of tumor-bearing mice and rats. How...