نتایج جستجو برای: and classification scale lat
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The latency-associated transcript (LAT) is the only herpes simplex virus type 1 (HSV-1) gene that is abundantly transcribed during latency. Plasmids expressing LAT inhibit apoptosis induced by etoposide and ceramide in transiently transfected cells. LAT also inhibits apoptosis in trigeminal ganglia of rabbits and promotes spontaneous reactivation, suggesting these events are coupled. In this st...
in this study which has been carried out from 1996 until 1997 soluble latex agglutination antigen was prepared from L, donovani,sudan(s-1) by culturing in special media,harvesting,and later solubilizing by freezing and thawing.the antigen were futher prepared by high speed centrifugation.after measurement of the protein (lowry method) concentration of the antigen was set at 2.2 mg/ml,the antige...
The herpes simplex virus type 1 (HSV-1) latency-associated transcript (LAT) gene is essential for the high spontaneous and induced reactivation phenotype of HSV-1 in the rabbit ocular model and for the high induced reactivation phenotype in the mouse ocular model. Recently we showed that LAT has an antiapoptosis function, and we hypothesized that LAT's ability to inhibit apoptosis played an imp...
The Large Area Telescope (LAT) on-board the Fermi Gamma-ray Space Telescope is a pair-conversion telescope designed to survey the gamma-ray sky from 20 MeV to several hundreds of GeV. In this energy band there are no astronomical sources with sufficiently well known and sharp spectral features to allow an absolute calibration of the LAT energy scale. However, the geomagnetic cutoff in the cosmi...
The linker molecule LAT is a critical substrate of the tyrosine kinases activated upon TCR engagement. Phosphorylated LAT binds Grb2, PLC-gamma1, and other signaling molecules. We demonstrate that human LAT is palmitoylated and that palmitoylated LAT predominantly localizes into glycolipid-enriched microdomains (GEMs). Although the LAT transmembrane domain is sufficient for membrane localizatio...
In its first three months of operations, the Fermi Gamma-ray Observatory has detected approximately one quarter of the radio-flux limited MOJAVE sample of bright flat-spectrum AGN at energies above 100 MeV. We have investigated the apparent parsec-scale jet speeds of 26 MOJAVE AGN measured by the VLBA that are in the LAT Bright AGN Sample (LBAS). We find that the γ-ray bright quasars have faste...
background: in diagnostic radiology there are two reasons for measuring or estimating radiation doses to patients. firstly measurements provide a means for setting and checking standards of good practice as an aid to the optimization of patient protection. secondly estimates of the absorbed dose to tissue and organs in the patients. materials and methods: a total of 2382 patients were studied t...
Mice deficient in the adaptor Src homology 2 domain-containing leukocyte phosphoprotein of 76 kD (SLP-76) exhibit a bleeding disorder and lack T cells. Linker for activation of T cells (LAT)-deficient mice exhibit a similar T cell phenotype, but show no signs of hemorrhage. Both SLP-76 and LAT are important for optimal platelet activation downstream of the collagen receptor, GPVI. In addition, ...
primary and widely in use computed tomography (ct) dose descriptor is a volumetric ct dose index (ctdiv) that is usually measured by a pencil ionization chamber with active length of 100mm and polymethyl methacrylate (pmma) phantom. ctdiv depends on scan parameters such as mas, kv, collimation, tube rotation time but is independent of patient’s size and shape. for the purpose of a good estimati...
The adapter molecule linker for activation of T cells (LAT) plays a crucial role in forming signaling complexes induced by stimulation of the T cell receptor (TCR). These multi-molecular complexes are dynamic structures that activate highly regulated signaling pathways. Previously, we have demonstrated nanoscale structure in LAT-based complexes where the adapter SLP-76 (also known as LCP2) loca...
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