Objective(s): We aimed to investigate the influence of transient receptor potential channel 3 (TRPC3) on lipopolysaccharide-induced (LPS) preterm delivery mice. Materials and Methods: Mice were randomly assigned to the four groups: an unpregnant group, a mid-pregnancy group (E15), a term delivery group, and an LPS-induced preterm delivery group (intraperitoneal injection LPS at 15 days). Uterin...

introduction: the main reason for choosing cesarean delivery is to save the life or health of the mother and her baby. however, cesarean is not without complications, either for the mother or the baby. it is well documented that cesarean rate in iran is higher than other developing countries and mother’s request reported the main influencing factor. this study carried out to find the relative f...

the application of chemotherapy in cancer treatment has been limited due to cause side effects such as toxicity against normal cells and drug resistance. in recent years, numerous studies have been focused on using natural products with chemotherapeutic drugs to enhance therapeutic efficiency and reduce cytotoxicity. on the other hand, encapsulation of drugs into nanoparticles (nps) can improve...

abstract background: data was reported in iran in 2013 has shown that almost 42 percent of deliveries in public hospitals and 90 percent in private hospitals were carried out with cesarean section. this high rate of cesarean requires careful consideration. it seems that making decision for cesarean is done under the influence of cultural perceptions and beliefs. so, this study was conducted to ...

breast feeding has a great impact on the infant morbidity and mortality. according to pakistan demographic and health survey (pdhs) infant mortality rate is 78 deaths per 1,000 live births. world health organization recommends that exclusive breast feeding for six months can decrease infant mortality rate by one-third. the objective of the study was to find out how the mode of delivery had impa...

background: the poor permeability of the plasma and nuclear membranes to dna plasmids are two major barriers for the development of these therapeutic molecules. therefore, success in gene therapy approaches depends on the development of efficient and safe non-viral delivery systems. objectives: the aim of this study was to investigate the in vitro delivery of plasmid dna encoding hpv16 e7 gene ...

background & aim: preterm delivery is one of the most important problems in pregnancy, as it is the primary cause of 75% of prenatal mortality and morbidities. this study aimed to determine the prevalence and risk factors for preterm delivery in tehran, iran. methods:in this cross-sectional study performed in eight random hospitals from five different regions of tehran (north, south, west, east...

conclusions there is no statistically significant relationship between preterm delivery and type of sludge. results the prevalence of preterm delivery was 14/3%. the frequencies of term delivery in mothers with dense, light and no sludge were 78/6%, 82/1% and 96/4 % respectively, and for preterm delivery they were 21/4%, 17/9% and 3/6% respectively. but there was no statistically significant re...