The efficacy of Andrographis paniculata (AP) extract was studied on atrazine induced hepatic damage in rats. Ethanolic extract of AP (150mg/kg body weight) was found to protect the male wistar rats from hepato toxic action of atrazine as evidence by significant reduction in the level of lipid peroxidation and increased the antioxidant defense system activity in the atrazine intoxicated rats. Ho...

Andrographis paniculata Nees.,a member of the family Acanthaceae is a plant commonly used by the local people, for the treatment of common cold, liver diseases, snake bite and some skin infection. The aerial part of the plant was screened for their phytochemical properties and antimicrobial activity. Antimicrobial activity of leaf extract of Andrographis paniculata, was studied using different ...

Effect of oral administration of aqueous leaf extract of Kalmegh (Andrographis paniculata) (250 mg/kg body weight/day) on the male reproductive organs of the wild Indian house rat (Rattus rattus) was investigated and its activity was noticed at 30th and 45th days of post treated animals. The treatment had no severe effect on body weight and the reproductive organs weight of rats. In treated rat...

Andrographis paniculata ethanolic extract was evaluated to screen the effect on insulin resistance using a combination of fat-fed diet and low dose streptozotocin. The glucose-insulin index as a measure of insulin action on glucose disposal rate was calculated during the intraperitoneal glucose tolerance test. Oral administration of 1000 mg/kg extract to rats was able to cause a significant (p<...

A rapid and sensitive silver ion high-performance liquid chromatographic (Ag[I]-HPLC) method is developed for the simultaneous determination of the biologically active diterpenoids andrographolide, 14-deoxy-11,12-didehydroandrographolide, 14-deoxyandrographolide, and neoandrographolide in Andrographis paniculata Nees. HPLC is carried out for determining andrographolide and its derivatives with ...

Aim: The research was carried out to investigate the analgesic and anti-inflammatory effects of ethanol extract of Desmodium pauciflorum, Mangifera indica and Andrographis paniculata leaves. Materials and Methods: In order to assess the analgesic and anti-inflammatory effects acetic acid induced writhing response model and carrageenan induced paw edema model were used in Swiss albino mice and W...