SUMMARY Fucosidosis is a rare autosomal recessive lysosomal storage disease with the main clinical findings of progressive neuromotor deterioration, seizures, coarse facial features, dysostosis multiplex, angiokeratoma corporis diffusum, visceromegaly, recurrent respiratory infections, and growth retardation. Fucosidosis type I rapidly evolves toward a progressive neurologic deterioration and d...

Angiokeratomas are vascular malformations that usually appear as multiple or solitary cutaneous plaques. Several clinical variants have been described, with the same underlying histopathological lesion. Mucosal involvement, including the oral cavity, is occasionally found either as a component of the systemic variety, called angiokeratoma corporis diffusum, or associated with cutaneous lesions ...

only able to apply a single session in the present case owing to the appearance of side effects, and this may explain the incomplete response obtained. However, it is also possible that the immunomodulatory effect of PDT and the inflammation already present in the lesion (visible in the clinical and histological images) may have favored a good therapeutic response with just 1 session. Ulceratio...