Inhibiting insulin/IGF-1 signalling extends lifespan and delays age-related disease in species throughout the animal kingdom. This life-extension pathway, the first to be defined, was discovered through genetic studies in the small roundworm Caenorhabditis elegans. This discovery is described here.

For the past 20 years genetical methods have gradually been made more and more familiar to the practical breeders of plants and animals, upon whom the improvement for human use of the domesticated animals and cultivated plants finally depends. During this period it has become increasingly clear that the hereditary mechanism is well represented by the Mendelian scheme, as extended mainly by the ...

Territory formation is ubiquitous throughout the animal kingdom. At the individual level, various behaviours attempt to exclude conspecifics from regions of space. At the population level, animals often segregate into distinct territorial areas. Consequently, it should be possible to derive territorial patterns from the underlying behavioural processes of animal movements and interactions. Such...