OBJECTIVE Psychotic symptoms are common in the population and index risk for a range of severe psychopathological outcomes. We wished to investigate functional connectivity in a community sample of adolescents who reported psychotic symptoms (the extended psychosis phenotype). METHOD This study investigated intrinsic functional connectivity (iFC) during resting-state functional magnetic reson...

Background. Adolescent marijuana use is associated with structural and functional differences in forebrain regions while performing memory and attention tasks. In the present study, we investigated neural processing in adolescent marijuana users experiencing rewards and losses. Fourteen adolescents with frequent marijuana use (>5 uses per week) and 14 nonuser controls performed a computer task ...

introduction: to recognize the myelinated nerve fibers of the external and extreme capsules in human brain. materials and methods: 10 adult and normal brains (20 hemispheres) from both sexes were studied using 15 mm serial secions in all three cardinal planes after fixation and processing. these sections were stained by klüver – barrera and heidenhin – woelcke methods. results: some fibers from...

The cover image is based on the Research Article Topographic gradients define projection patterns of claustrum core and shell in mice by Brian A. Marriott et al., https://doi.org/10.1002/cne.25043.

This paper present a new hypothesis as to the function of the claustrum. Our basic premise is that the claustrum functions as a detector and integrator of synchrony in the axonal trains in its afferent inputs. In the first place an unexpected stimulus sets up a processed signal to the sensory cortex that initiates a focus of synchronized gamma oscillations therein. This focus may then interact ...

The claustrum is a functionally and structurally complex brain region, whose very spatial extent remains debated. Histochemical-based approaches typically treat the as relatively narrow anatomical region that primarily projects to neocortex, whereas circuit-based can suggest broader containing projections neocortex other regions. Here, in mouse, we took bottom-up cell-type-specific approach com...

The claustrum has been proposed as a possible neural candidate for the coordination of conscious experience due to its extensive “connectome”. Herein we propose that the claustrum contributes to consciousness by supporting the temporal integration of cortical oscillations in response to multisensory input. A close link between conscious awareness and interval timing is suggested by models of co...

Comparatively little is known about the connexions of the claustrum; two recent reviews (Rae, 1954; Berke, 1960) have summarized the evidence available from studies of normal and Marchi-stained material, and have emphasized the inadequacy of our understanding of the basic organization of the connexions of the claustrum. In view of the paucity of knowledge it was considered worthwhile to place o...

The mammalian claustrum is involved in processing sensory information from the environment. The claustrum is reciprocally connected to the visual cortex and these projections, at least in carnivores, display a clear retinotopic distribution. The visual cortex of dolphins occupies a position strikingly different from that of land mammals. Whether the reshaping of the functional areas of the cort...