INTRODUCTION Fluocinolone acetonide (FAc) intravitreal implant (ILUVIEN(®); Alimera Sciences Limited, Aldershot, UK) has been approved in the UK for the treatment of chronic diabetic macula edema, insufficiently responsive to available therapies. It is inserted into the vitreous cavity through a 25-gauge needle. Migration of the implant to the anterior chamber (AC) can occur through gaps in the...

Traumatic brain injury can cause various pathological conditions both in the eyeball and cranial cavity. The presented clinical case demonstrates features of differential diagnosis direct carotid-cavernous fistula secondary post-traumatic glaucoma. Direct is formation a communication between internal carotid artery cavernous sinus discharge arterial blood into it. first symptom pulsating noise ...

Every eye surgeon has experienced – or will experience – that sinking feeling when the posterior capsule is ruptured and vitreous comes forward into the anterior chamber. At that moment everything changes, including the heart rate of the surgeon and the possible outcome for the patient. But all is not lost. If the theatre team are well prepared, the situation can be managed calmly and professio...

The vitreous is an optically clear, collagenous extracellular matrix that fills the inside of the eye and overlies the retina. (1,2) Abnormal interactions between vitreous substructures and the retina underlie several vitreoretinal diseases, including retinal tear and detachment, macular pucker, macular hole, age-related macular degeneration, vitreomacular traction, proliferative vitreoretinopa...

Using pigmented rabbits, two fluorophotometric methods for measuring aqueous flow were compared. A corneal depot of dye was used to measure aqueous flow in one eye of each rabbit while the vitreous depot method of Johnson and Maurice was used to measure aqueous flow over the same period in the fellow eye. After intravenous administration of acetazolamide or mannitol, during the first hour after...

PURPOSE Recent studies have illuminated the vitreous proteome as a potentially important diagnostic tool that will predict disease progression and response to treatment, in eyes with retinal disease. Studies to date have demonstrated correlations of protein levels between vitreous and aqueous humor. Because these results are un-expected and analysis was only done on a few endpoints, the present...

BACKGROUND AND OBJECTIVE This study examines the value of ultrasound elastography for the examination of ocular and periocular structures. SUBJECTS AND METHODS Five patients, aged 22 to 75 years, who each had one blind eye were included. Patients underwent ultrasound elastography of their blind eye and periocular tissues using a 7-13 MHz probe. Strain grayscale and color-coded elastographic m...

over 75% of cases.5-7 This process is characterised by cellular proliferation on both surfaces of the detached neuroretina, on the posterior vitreous face, and within the vitreous base resulting in the formation of contractile periretinal membranes. It is estimated to occur in 5-10% of all rhegmatogenous retinal detachments.7 Initial clinical observations emphasised cellular activity in, and re...

Purpose: We report a case of macular, serous retinal detachment associated with hypotony in patient pachychoroid disease developing after Ahmed valve implantation.Case summary: A 77-year-old male visited our clinic uncontrolled intraocular pressure (IOP; 32 mmHg) his left eye despite maximal tolerable medical therapy. prolapsed vitreous filled the anterior chamber. Swept-source optical coherenc...

Clinically in both the congenital and the acquired ocular disease, there is an acute focal chorioretinitis having its active onset of recurrence between ages 11 and 40 years old. Lesions may be single, variable in size, and are usually posterior to the equator. There is exudation into the vitreous and flare and cells in the anterior chamber. Vitreous may detach from the retina, with hemispheric...