نتایج جستجو برای: anti hypertensive agent
تعداد نتایج: 705297 فیلتر نتایج به سال:
Lisinopril dihydrate (angiotensin converting enzyme inhibitor) is a lysine derivative of enalaprilat and does not require hydrolysis to exert pharmacological activity. It has an extensive hepatic first pass metabolism resulting in a bioavailabil-ity of 6-60%. To overcome the poor bioavailability of the drug, transdermal patches have been prepared. The present study also aims at optimizati...
1. Oral and intravenous administration of metoprolol to adult spontaneously hypertensive rats (SHR) with established hypertension lowered arterial blood pressure within 4 days of treatment. 2. Steady state plasma concentrations of metoprolol were similar to those of patients during anti-hypertensive treatment with this drug. 3. The neuroeffector function of portal veins of SHR treated orally fo...
We have previously demonstrated that acacia polyphenol (AP) exerts strong anti-obesity, anti-diabetic, and anti-atopic dermatitis effects. In the present study, we investigated the anti-hypertensive effects of AP. Spontaneously hypertensive rats (SHR) with hypertension and control Wistar Kyoto rats (WKY) were used. WKY and SHR were fed AP-containing food or AP-free food (control group) ad libit...
Adlay (Coix larchryma-jobi L.) was the commonly used Traditional Chinese Medicine (TCM) with high content of seed storage protein. The hydrolyzed bioactive oligopeptides of adlay have been proven to be anti-hypertensive effective components. However, the structures and anti-hypertensive mechanism of bioactive oligopeptides from adlay were not clear. To discover the definite anti-hypertensive ol...
ABSTRAK Hipertensi adalah keadaan pada seseorang dimana terjadinya peningkatan tekanan darah yang melebihi batas normal telah ditentukan yaitu sistolik ≥ 140 mmHg dan diastolik 90 mmHg. Gaya hidup merupakan faktor utama meningkatkan penyakit hipertensi, salah satu penyebabnya kurang dalam melakukan aktifitas fisik, seperti olahraga. Salah fisik atau olahraga bisa dilakukan penderita hipertensi ...
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