نتایج جستجو برای: anti infective agents
تعداد نتایج: 685202 فیلتر نتایج به سال:
Many publications in the past 10 years have emphasised the difficulties of evaluating anti-infective drugs and the need for well-designed clinical trials in this therapeutic field. The clinical development of sparfloxacin in Europe, involving more than 4000 patients in ten countries, provided the opportunity to implement a methodology for evaluation and statistical analyses which would take int...
Recent reports of the biochemical, anti-infective, antiallergic, contraceptive, emotional, and economic advantages of breastfeeding have aroused vigorous efforts to increase this practice; indeed, in 1979, the week from 3 June to 9 June was International Breast-feeding Week. Most researchers accept that the increasing use of artificial feeding contributes much to the widespread infantile malnut...
In the UK Government's 1993 review of science and technology the statement is made that "the interval between scientific discovery and practical application is diminishing".' Two changes might explain such an acceleration of the acceptance of scientific innovation. Alterations may have occurred in the way that scientific ideas are spread, with concomitant increases in their rates of diffusion. ...
PURPOSE To quantify the use of multiple and prolonged antibiotics and anti-infective drug therapy in clinical patients in a 144-bed hospital. METHODS Adult patients (2,790 patients with 3,706 admissions over a period of 19 months) were investigated prospectively regarding treatment with anti-infective agents. The mean age was 57.4 (range, 18.8-97 years), and 54.3% were females (2012). RESUL...
In 55 instances, a single proprietary (trade) name has been used to market > or = 2 distinct generic anti-infective agents. In some cases, one trade name represents 2 different drugs in the same country--or even marketed by the same manufacturer. Some unrelated drugs and poisonous substances are also manufactured under trade names assigned to anti-infectives. The use of proprietary names in the...
Detection of adverse drug reactions (ADRs) in hospitals provides an important measure of the burden of drug related morbidity on the healthcare system. Spontaneous reporting of ADRs is scare and several obstacles to such reporting have been identified formerly. This study aimed to determine the role of clinical pharmacy residents in ADR reporting within a hospital setting.Clinical pharmacy resi...
Introduction Heparanase is an endo-b-glucuronidase that cleaves highly potent heparan sulfate (HS) from its proteoglycan, thereby triggering the inflammatory response in [1]. Thus, new anti-infective agents that interact with heparanase may be promising tools for sepsis therapy. As a novel anti-infective agent, peptide 19-2.5 (pep2.5) belongs to the class of synthetic anti-lipopolysaccharide pe...
Detection of adverse drug reactions (ADRs) in hospitals provides an important measure of the burden of drug related morbidity on the healthcare system. Spontaneous reporting of ADRs is scare and several obstacles to such reporting have been identified formerly. This study aimed to determine the role of clinical pharmacy residents in ADR reporting within a hospital setting.Clinical pharmacy resi...
Anti-infective and anticancer drugs share the serious problem that over time resistance develops to their effects leading clinical obsolescence. Research at University of Strathclyde has discovered a platform anti-infective based upon minor groove binders for DNA have exceptional resilience development in target organisms (bacteria, fungi, parasites). This property is associated with fact (S-MG...
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