This study was applied on 90 tuberculosis patients admitted in the Babylon Center of Tuberculosis and Chest Diseases Hilla, Iraq. They were divided into four groups; 50 with Pulmonary, 40 Extra pulmonary,20 people as healthy contact group 20 control group. Blood samples collected from to estimate Anti Ascrais lumbricoides-IgG , also Zinc copper level spectrophotometerically estimated. The ages ...

background and objectives: esat-6 (6-kdaearly secretory antigenic target) and cfp-10 (10-kda culture filtrate protein) have been described as dominant antigens recognized by t-cells and considered as virulence factors in mycobacterium tuberculosis . the aim of this study was to clone, express and purify recombinant esat-6 andcfp-10 proteins of m. tuberculosis in soluble form. materials and meth...

Objective: Ocular tuberculosis is still considered to be a controversial issue in terms of both terminology and diagnostic criteria treatment options. There no common diagnostic/treatment algorithm even though new approaches exist.In this study, the results “presumed ocular patients” are evaluated. Materials Methods: Anti-tuberculosis was given cases who had latent infection, other diagnosis di...

Aim: The quality of tuberculosis diagnosis service is indispensable for early infection control and preventing unnecessary anti-tubercular therapy use. TB in Sudan mainly relies on detecting tubercule bacilli using the Ziehl-Neelsen (ZN) staining technique. Thus, current study aimed to compare ZN microscopy with GeneXpert diagnosing pulmonary (PTB) laboratories center Khartoum state, Sudan. Met...

The aim of this study was to determine the association of n-acetyltransferase-2 polymorphisms and anti-tuberculosis drug-induced hepatotoxicity in Iranian pulmonary tuberculosis patients. Acetylating phenotypes was studied in 50 Iranian pulmonary tuberculosis patients using metabolic ratio of plasma acetyl-Isoniazid to Isoniazid. The association between hepatotoxicity and the n-acetyltransferas...

Simplifying and shortening treatment for drug-sensitive tuberculosis and providing new treatment options for drug-resistant tuberculosis constitute two principal goals in the development of novel drugs for tuberculosis. Demonstration of clinical efficacy in drug-sensitive tuberculosis is challenging, given high success rates for existing regimens, concerns about substituting an investigational ...

The aim of this study was to determine the association of n-acetyltransferase-2 polymorphisms and anti-tuberculosis drug-induced hepatotoxicity in Iranian pulmonary tuberculosis patients. Acetylating phenotypes was studied in 50 Iranian pulmonary tuberculosis patients using metabolic ratio of plasma acetyl-Isoniazid to Isoniazid. The association between hepatotoxicity and the n-acetyltransferas...

this study was planned to determine hiv seroprevalence among pulmonary tuberculosis patients, to characterize the isolated mycobacteria into typical and atypical strains and to evaluate the drug resistant pattern of mycobacterial isolates. the study aims to correlate multidrug resistance (mdr) and hiv seropositivity status in pulmonary tuberculosis patients. during the year 1994-1997, 750 pulmo...

Magnesium is an essential metal that has important roles in physiological function of the body organs. Ethambutol is an oral antitubercular agent with chelating effects owing to its chemical structure. The aim of present study is to determine whether ethambutol usage can alter serum magnesium concentration in patients with pulmonary tuberculosis. Sixty patients with diagnosis of pulmonary tuber...