نتایج جستجو برای: anticancerous activity
تعداد نتایج: 1134415 فیلتر نتایج به سال:
Background Biosynthesized copper nanoparticles (CuNPs) are eco-friendly, cost-effective, and biocompatible agents reported for extensive biomedical bioengineering applications. Different chemical synthesis approaches have been established recently, with challenges of higher toxicity high cost involved in the process. Green synthesized emerged was extensively to address faced by traditional proc...
Matrix metalloproteinase-2 (MMP-2) plays a critical role in tumor cell invasion and metastasis. Inhibitors of this enzyme effectively suppress tumor metastasis in experimental animals and are currently being tested in clinical trials. MMP-2 transcriptional regulation is a part of a delicate balance between the expression of various extracellular matrix (ECM) constituents and ECM degrading enzym...
L-asparaginase is an enzyme that catalyzes the conversion of L-asparagine to L-aspartate and ammonia. The important application of the L-asparaginase enzyme is in the treatment of acute lymphoblastic leukemia, Hodgkin disease, acute myelocytic leukemia, chronic lymphocytic leukemia, lymphosarcoma treatment, reticulosarcoma and melanosarcoma. In the present study, the L-asparaginase from Erwinia...
Heparanase is an endo-β-D-glucuronidase that cleaves heparan sulfate (HS) side chains at a limited number of sites, activity that is strongly implicated with cell invasion associated with cancer metastasis, a consequence of structural modification that loosens the extracellular matrix barrier. Heparanase activity is also implicated in neovascularization, inflammation, and autoimmunity, involvin...
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