OBJECTIVE To study the correlation between fungal colonization and bacterial pneumonia and to test the effect of antifungal treatments on the development of bacterial pneumonia in colonized rats. DESIGN Experimental animal investigation. SETTING University research laboratory. SUBJECTS Pathogen-free male Wistar rats weighing 250-275 g. INTERVENTIONS Rats were colonized by intratracheal ...

Spherical silver nanoparticles (nano-Ag) were synthesized and their antifungal effects on fungal pathogens of the skin were investigated. Nano-Ag showed potent activity against clinical isolates and ATCC strains of Trichophyton mentagrophytes and Candida species (IC80, 1-7 microg/ml). The activity of nano-Ag was comparable to that of amphotericin B, but superior to that of fluconazole (amphoter...

background : dermatophytosis is the common cutaneous infections in humans and animals, which is caused by the keratinophylic fungus called dermatophytes. in recent years , drug-resistance in pathogenic fungi, including dermatophytes to the current antifungal have been increased . the aim of this study was to evaluate the antifungal efficacy of agnps against microsporum canis, trichophyton menta...

objective: in order to use natural compounds in controlling plant pests and diseases, many researchers in recent years have studied the antifungal effects of essential oils and plant extracts.  the purpose of this study was to investigate the chemical composition and antifungal effects of echium khuzestanium and marubbium anisodan extracts. methods: after extraction and preparation of different...

INTRODUCTION Microorganisms and microbial products are the main etiologic factors in pulp and periapical diseases. The present study aimed to compare the antifungal activity of two different sealers, AH-26 and MTA Fillapex against three strains of Candida, 24, 48, 72 h and 7 days after mixing. METHODS AND MATERIALS The microorganisms used in this study were Candidia albicans (ATCC 10231), Can...

Bu çal??mada, Türkiye'nin Hatay ilinin farkl? bölgelerinde do?al olarak yeti?en Foeniculum vulgare ve Laurus nobilis gibi bitkilerden elde edilen uçucu ya?lar?n, toprak kaynakl? mantar (Sclerotinia sclerotiorum) hastal?k etkenlerine kar?? in vitro antifungal etkinli?i ara?t?r?lm??t?r. Farkl? konsantrasyonlardaki ya?lar?n faz?, doza ba?l? bir ?ekilde miselyal geli?meyi inhibe etmi?tir. L. ya?lar...

Objective: To investigate the antifungal activity of crude extract of leaves of Tamarix dioica tree. Material and Methods: Antifungal activity of crude extract of T. dioica leaves was studied. The extract was dissolved in Dimethyl Sulfoxide, then six strains of fungi were subjected to crude extract separately by agar tube dilution method. Inhibitory effect of extract in millimeters was determin...

This technical report describes the development of an aptamer for sensing azole antifungal drugs during therapeutic drug monitoring. Modified synthetic evolution of ligands through exponential enrichment (SELEX) was used to discover a DNA aptamer recognizing azole class antifungal drugs. This aptamer undergoes a secondary structural change upon binding to its target molecule, as shown through f...

OBJECTIVE To isolate the active fraction from crude extract of Gracilaria changii and to determine its in vitro antifungal activity. MATERIALS AND METHODS The active fraction was isolated from the crude extract of G. changii by various purification procedures such as column chromatography, thin layer chromatography, bioauthograph etc. The in vitro antifungal activity (Candida albicans) of the...