leptospirosis is one of the most prevalent zoonotic diseases worldwide. currently, multivalent whole-cell leptospiral vaccines can induce protection against leptospirosis. therefore, preparation and formulation of new generations of vaccines that can stimulate long-term immunity for leptospirosis control are essential. the aim of this study was to prepare and characterize alginate microspheres ...

the liver fluke fasciola hepatica causes fascioliasis, a liver disease in most part of the world and particularly in north of iran. diagnosis of the diseases is anchored in coprological manner but serological methods are preferable due to some obscurities. in this study, sera obtained from human patients infected with fasciola hepatica were tested by the enzymelinked immunotrotransfer blot (eit...

To improve cancer chemotherapy, a better understanding of the molecular mechanisms of drug resistance is essential. To identify the molecules responsible for drug resistance that is unrelated to MDR1 or MRP gene products, a eukaryotic expression cDNA library of cis-diamminedichloroplatinum(II) (CDDP)-resistant ovarian cancer TYKnuR cells was introduced into Cos-7 cells. After repeated CDDP sele...