نتایج جستجو برای: antihelmintic activity
تعداد نتایج: 1134393 فیلتر نتایج به سال:
Purpose: Glioblastoma is a highly malignant, invariably fatal brain tumor for which effective pharmacotherapy remains an unmet medical need. Experimental Design: Screening of a compound library of 160 synthetic and natural toxic substances identified the antihelmintic niclosamide as a previously unrecognized candidate for clinical development. Considering the cellular and interindividual hetero...
Ferula assa-foetida L. is distributed throughout central Asia and Mediterranean area and grows wildly in Iran and Afghanistan. Asafoetida is an oleo-gum-resin that is the exudates of the roots of Ferula assa-foetida and some other Ferula species. In Iranian traditional medicine, asafoetida is considered to be sedative, analgesic, carminative, antispasmodic, diuretic, antihelmintic, emmenagogue ...
Traditional system of medicinal consists of large number of plants with various medicinal and pharmacological importances and hence represents a priceless tank of new bioactive molecules. Alpinia galanga (Linn.) Pierre is one amongst these, found all over the world. It is commonly known as ‘Kulanjan’, and has been recognized in different traditional system of medicines for the treatment of vari...
In the practice of chemical-toxicological analysis, cases poisoning people with certain antihelmintic drugs have become more frequent. Some antihelmintics are on WHO Model List Essential Medicines, World Health Organization's list essential medicines, which lists most effective, safest and affordable medicines. Despite worldwide recognition, effectiveness, availability low cost, they an importa...
Thiabendazole (TBZ), an antifungal and antihelmintic benzimidazole derivative, after 6 min treatment with a 0.1 m M aqueous solution enhances C 0 2 release in intact potato tubers for up to two hours. There are also indications for a reduced water permeability of isolated periderm layers from TBZ treated potato tubers. Potato slices (ca. 3 mm thick) or discs (with ca. 5 mm diameter) from potato...
Most Brazilian dairy production is conducted by small holders whose general management skills and feeding programs are often deficient. One common problem directly attributed to underfeeding is that heifers rarely reach sexual maturity before 15 months of age. Groups of growing heifers were treated to detect the effects of protein supplementation and antihelmintic treatment on sexual maturity. ...
Genus Iris is well known rhizomatous herb belonging to family Iridaceae and is represented by 260 species [1]. Iris species have immense medical importance in indigenous systems of medicine and are used in the treatment of liver dysfunction, inflammation, bacterial and viral infections [2,3]. Externally root in powder or poultice is used as an application to sores and pimples [2]. Rhizomes of I...
BACKGROUND Protein aggregation is a hallmark of many neurodegenerative diseases and has been linked to the failure to degrade misfolded and damaged proteins. In the cell, aberrant proteins are degraded by the ubiquitin proteasome system that mainly targets short-lived proteins, or by the lysosomes that mostly clear long-lived and poorly soluble proteins. Both systems are interconnected and, in ...
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