Proteins and peptides of housefly larvae (HFL) have potential applications in food therapy. The fate HFL proteins following human gastrointestinal (GI) digestion is unknown. This study adopted a computational approach to discover released from upon GI digestion. In silico eight major 783 peptides. comprised 243 exhibiting 13 types bioactivities. Ninety-two single-function anti-dipeptidyl peptid...

Background: The high blood pressure (BP) or hypertension is a widely prevalent disease and its costs are very high, many studies about the relationships between BP health conditions have been done. We need to know precise distributions of factors affecting BP. Data Methods: analyzed using 12,877,653 observations obtained from JMDC Claims Database. that may affect by regression models 4,615,346 ...

OBJECTIVE To evaluate the behavior of blood pressure during exercise in patients with hypertension controlled by frontline antihypertension drugs. METHODS From 979ergometric tests we retrospectively selected 49 hypertensive patients (19 males). The age was 53+/-12 years old and normal range rest arterial pressure (< or = 140/90 mmHg) all on pharmacological monotherapy. There were 12 on beta b...

Peptide hydrolysates of silkworm pupae protein with molecular weight of less than 5000 Da were prepared by ultrafiltration. The extracted peptide hydrolysates of silkworm pupae protein had inhibitory action on angiotensin-I-converting enzyme activity in vitro. The hydrolysates were orally administered to spontaneously hypertensive rats (SHR) in one period and long-term (four weeks). The results...

BACKGROUND Pseudohypertension (PHT) can cause adverse effects in the elderly owing to administration of antihypertension therapy. The present study aimed to determine the prevalence of PHT in the elderly and associated risk factors to investigate a noninvasive method of detection of PHT. METHODS We recruited 151 patients (age ≥60 years) who underwent coronary angiography. Demographic and clin...

Background: Antihypertensive agents used during pregnancy may vary from institution to and depend on resource availability. Objective: This study aimed determine the profile of antihypertensive drugs in low-middle-income countries impact these maternal fetal outcomes. Materials Methods: is a retrospective hypertensive pregnant patients admitted emergency unit at tertiary referral Hospital Indon...