A simple microbiological method to identify antimicrobial agents in urine is described. Of 1,514 consecutive urine specimens received from general practitioners, 302 (19.94%) contained antimicrobial activity. The antibacterial agent was identified confidently in 284 of these. Surprisingly, 83 (5.48%) urine specimens contained an antimicrobial substance not usually used in the treatment of urina...

Brochotrix campestris ATCC 43754 produces a bacteriocin inhibitory towards Brochothrix thermosphacta, lactobacilli, Listeria spp., and other gram-positive bacteria. This antimicrobial agent is heat stable, sensitive to proteases, catalase insensitive, and free of organic acids. No phage particles were detected by transmission electron microscopy. Muramidase activity was not detected in the prep...

Ruthenium coordination compounds have demonstrated a promising anticancer and antibacterial activity, but their poor water solubility low stability under physiological conditions may limit therapeutic applications. Physical encapsulation or covalent conjugation with polymers overcome these drawbacks, generally involve multistep reactions purification processes. In this work, the activity of pol...