introduction : halitosis is a common problem that affects a large portion of the population worldwide. the origin of this condition is oral in 90% of cases and systemic in 10% of cases. the foul odor is caused mainly by volatile sulfur compounds produced by gram-negative bacteria. however, it has recently been found that anaerobic gram-positive bacteria also produce hydrogen sulfide (h 2 s) in ...

Aim: to evaluate the adjunctive effects of photodynamic therapy (aPDT) on nonsurgical mechanical treatment in patients with periodontitis. Materials and methods: The search strategy was conducted according PRISMA guidelines answer research questions regarding effectiveness aPDT association non-surgical periodontal therapy. mean values standard deviations were collected by data extraction. A des...

Objectives: This study aimed to assess the efficacy of shockwave-enhanced emission photoacoustic streaming (SWEEPS) plus antimicrobial photodynamic therapy (aPDT) using indocyanine green (ICG) for elimination Enterococcus faecalis biofilm from infected root canals. Materials and Methods: thirty sound human single-canal teeth were chosen standardized have 12 mm length. The canals shaped prepared...

Citation: Cieplik F, Steinwachs V-S, Muehler D, Hiller K-A, Thurnheer T, Belibasakis GN, Buchalla W and Maisch T (2018) Phenalen-1-one-Mediated Antimicrobial Photodynamic Therapy: Antimicrobial Efficacy in a Periodontal Biofilm Model and Flow Cytometric Evaluation of Cytoplasmic Membrane Damage. Front. Microbiol. 9:688. doi: 10.3389/fmicb.2018.00688 Phenalen-1-one-Mediated Antimicrobial Photody...

Treatment of mucocutaneous and cutaneous Candida albicans infections with photosensitizing agents and light, termed photodynamic therapy (PDT), offers an alternative to conventional treatments. Initial studies using the clinically approved photosensitizer Photofrin demonstrated the susceptibility of C. albicans to its photodynamic effects. In the present study, we have further refined parameter...

Biofilm have been found to be involved in a wide variety of microbial infections in the body, by one estimate 80% of all infections. A number of anti-biofilm strategies have emerged to prevent the colonization and formation of biofilms. However, there are four main intervention strategies in clinical practice for biofilm-associated infections. The first strategy is to prevent the initial microb...

Photodynamic therapy has been considered a potential antimicrobial modality against oral infections, including dental caries. A model to estimate the penetration of both photosensitizers and light through human dentin, a factor of interest in photodynamic therapy, is proposed. The photoacoustic spectroscopy technique was used to evaluate in vitro dentin permeability of three different photosens...

Minimization or elimination of antibiotic resistance in microbial species is an urgent need of the present times. Antimicrobial photodynamic therapy is a new therapeutic option through which development of resistance in microorganisms can be avoided. Interest in the use of photodynamic therapy to combat microbial infection is not only linked to the fact that this technique prevents antibiotic r...

INTRODUCTION The aim of this study is the evaluation of the effect of Antimicrobial Photodynamic Therapy with Radachlorin on Staphylococcus aureus and Escherichia coli. New windows are open in the antimicrobial field so-call Photodynamic therapy that incorporates a nonpoisonous photosensitizer (PS) with innocuous special wavelength photons to excite the PS. METHODS Two strains of bacteria use...