Antimicrobial preservatives are excipients added to multi-dose containers of both sterile and non-sterile drug products. Antimicrobial preservatives are used primarily to inhibit growth of microbial contamination occurring during the period of use. Demonstration of antimicrobial preservative effectiveness is required for these functional excipients. This article reviews key factors for consider...

background scrophularia striata (scrophulariaceae family) is an herbaceous plant that is traditionally used for treatment of microbial infections. objectives antimicrobial and antioxidant activity of different extracts (methanolic, ethanolic, aqueous and ethyl acetate) from s. striata aerial parts was evaluated. materials and methods the antimicrobial activity of different extracts from s. stri...

BACKGROUND & OBJECTIVES Reliable methods of detection of antimicrobial resistance are of paramount importance in the treatment and management of infections caused by Haemophilus influenzae. The objective of the present study was to compare and evaluate the performance of disc diffusion and E test (Epsilometer test) with agar dilution method for antimicrobial susceptibility testing of H. influen...

Sixty-two antimicrobial agents, including several combinations, were examined for stability at 56 degrees C for 30 min and 121 degrees C for 15 min, respectively. A microtiter broth dilution MIC test and an agar disk diffusion test served to test each chemo-agent for residual antimicrobial activity. Eleven drugs were partially heat-labile (MICs raised four- to eight-fold after autoclaving) and ...

The serum bactericidal test represents one of the few in vitro tests performed in the clinical microbiology laboratory that combines the interaction of the pathogen, the antimicrobial agent, and the patient. Although the use of such a test antedates the antimicrobial era, its performance, results, and interpretation have been subject to question and controversy. Much of the confusion concerning...

the plant salvadora persica is used for oral hygiene in many parts of the world. it has been suggested that it has antibacterial properties, in addition to its ability to mechanically remove plaques. the aim of this study was to assess the antimicrobial activity of the herbal product persica containing salvadora persica against periodontopathogens porphyromonas gingivalis and aggregatibacter ac...

INTRODUCTION Most current root-end filling materials do not provide a perfect seal. Thus, a microscopic space is likely to exist in the interface between walls of the root-end cavity and filling material, which allows microorganisms and their products to penetrate. In addition to good sealing ability and biocompatibility, root-end filling materials should ideally have some antimicrobial activit...

background: to evaluate the antimicrobial efficacy of four different hand sanitizers against staphylococcus aureus, staphylococcus epidermidis, pseudomonas aeruginosa , escherichia coli , and enterococcus faecalis as well as to assess and compare the antimicrobial effectiveness among fou different hand sanitizers. materials and methods: the present study is an in vitro study to evaluate antimic...

An antimicrobial validatory screening of short nosed tripod fish Triacanthus biaculeatus (Bloch, 1786) collected from the Visakhapatnam coastal waters, India is done in such a way T. biaculeatus muscle extracts were subjected for antimicrobial assay. Antimicrobial screening assay was done in five bacterial pathogens viz., Escherichia coli (MTCC-443), Salmonella typhi (MTCC-421), Pseudomonas aer...