the aim of the present study was to evaluate the pattern of vancomycin administration in the hematology-oncology ward of nemazee hospital, shiraz, iran. study criteria were developed to assess the several parameters involved in vancomycin therapy. these parameters include the appropriateness of drug usage, dosage, duration of therapy, monitoring for toxicity and serum concentration monitoring. ...

Drug-induced reticulate hyperpigmentation is uncommon. Including the patient described in this report, chemotherapy-associated reticulate hyperpigmentation has only been described in ten individuals. This paper describes the features of a woman with recurrent and metastatic breast cancer who developed paclitaxel-induced reticulate hyperpigmentation and reviews the characteristics of other oncol...

Regional antineoplastic drug delivery is not a new concept. Following the initial recognition that cytotoxic alkylating agents could cause shrinkage of tumor masses and a reduction in the quantity of malignant ascites in patients with advanced ovarian cancer, investigators in the 1950s instilled the drugs directly into the peritoneal cavity in an effort to treat the malignancy (1). Similarly, i...

Regional antineoplastic drug delivery is not a new concept. Following the initial recognition that cytotoxic alkylating agents could cause shrinkage of tumor masses and a reduction in the quantity of malignant ascites in patients with advanced ovarian cancer, investigators in the 1950s instilled the drugs directly into the peritoneal cavity in an effort to treat the malignancy (1). Similarly, i...

poly-drug use refers to the use of two or more substances at the one time or repeatedly. it is common among both recreational and regular drug users across the world. poly-drug use is a great contributor to the global number of deaths related to drug overdose. in this case, the likelihood of drug overdose and its pertaining complications in an individual is higher especially when benzodiazepine...

Erythromycin is a commonly used broad-spectrum antibiotic, but resistance to this antibiotic makes its use less effective. Considerable efforts, beside finding alternatives, are needed enhance antimicrobial effect and stability against bacteria. Tetrahedral framework nucleic acids (tFNAs), novel delivery vehicle with three-dimensional nanostructure, have been studied as carrying platform of ant...