ilex spinigera (aquifoliaceae) plant is an evergreen tree or shrub with thick glossy dark green leaves and red fruits. this plant has medicinal properties and has been used traditionally in northern iran for malaria treatment. the aim of this work is to evaluate the antioxidative activities and the inhibitory effect of i.spinigera on the oxidation of dna. we have found no reports about the popu...

background and objectives: otostegia persica (burm.) boiss. is an endemic plant of iran with various applications in traditional medicine which contains of several antioxidant constituents. this research was aimed to investigate the effect of hydroalcoholic extract from o. persica aerial parts in human umbilical vein endothelial cells (huvecs) using hydrogen peroxide (h2o2) as an inducer of oxi...

Materials and methods: Classical biochemical methods were used to determine plasma malondialdehyde (MDA), nitric oxide (NO), glutathione peroxidase (GSH-Px), catalase (CAT), superoxide dismutase (SOD), and glutathione (GSH) levels. Enzyme-linked immunosorbent assay was used to determine plasma insulin levels and reverse transcriptasepolymerase chain reaction was used to determine the levels of ...

objective: alchornea floribunda leaves are widely used in ethnomedicine for the management of immuno-inflammatory disorders. we investigated the in vivo and in vitro antioxidant activity of the leaf extract, fractions and isolated compounds of a. floribunda.materials and methods: the ethyl acetate fraction of the methanol leaf extract was subjected to several chromatographic separations to isol...

safety and beneficence of farm animal nutrition plays a great role in their healthy life which in turn have impact on human nutrition via diary or meat products. assessing safety and beneficence of vicia varibilis freyn and sint. which is chosen intrinsically by domesticated animals of kohgiluyehand boyerahmad iranis the aim of the present work. our results not only show no cytotoxic activity i...

A series of polysubstituted 1,4-dihydropyridines (4a-i) were designed and developed using Ph-B(OH)2 catalyst. Further, compounds confirmed by various spectroscopic techniques. After that all studied for molecular docking against the human peroxidase enzyme (1PRX). Results revealed many exhibited low binding score. To get a reference from study, synthesized molecules evaluated in vitro antioxida...

Elephantopus scaber is an herb widely used in folk remedies Vietnam, especially the treatment of liver disease. However, scientific studies evaluating activity and ability to treat disease a way are still very limited. This study evaluated antibacterial, antioxidant, acute toxicity hepatoprotective efficacy E. extracts. The extracts restricted growth 6 types bacteria, being particularly most ef...

a number of 6-hydroxy-2-benzylidene-3-coumaranones were synthesized from condensation of 6-hydroxy-3-coumaranone with appropriate aldehydes and were evaluated for their antioxidant activities. the antioxidant activity was assessed using two methods, including, 1,1-biphenyl-2-picrylhydrazyl (dpph) radical scavenging, and reducing power assays. some of the benzylidene coumaranones showed antioxid...

BACKGROUND Based on the pharmacological potency and structural features of succinimides, this study was designed to synthesize new ketoesters derivatives of succinimides. Furthermore, the synthesized compounds were evaluated for their possible anticholinesterase and antioxidant potentials. The compounds were synthesized by organocatalytic Michael additions of α-ketoesters to N-aryl maleimides. ...

background: the rosemary extract (re) possesses various antioxidant, cytoprotective and cognition-improving bioactivities. in this study, we postulated which doses of re have a more effect on the hippocampus of middle-aged rats.   methods : in this experimental study, thirty-two middle-aged male wistar rats were fed by different doses (50,100 and 200 mg/kg/day) of re (containing 40% carnosic ac...