In the developing embryo and fetus, endogenous or xenobiotic-enhanced formation of reactive oxygen species (ROS) like hydroxyl radicals may adversely alter development by oxidatively damaging cellular lipids, proteins and DNA, and/or by altering signal transduction. The postnatal consequences may include an array of birth defects (teratogenesis), postnatal functional deficits, and diseases. In ...

Setaria megaphylla (Steud) Dur & Schinz (Poaceae), a perennial grass used traditionally in the treatment of various diseases such as malaria was, investigated for antioxidative stress activity Plasmodium berghei-infected mice. The leaf extract (200-600 mg/kg) and fractions (hexane, dichloromethane, ethyl acetate methanol; 400 S. were hepatoprotective activities mice using modified suppressi...

Salinity-induced modulations in growth, photosynthetic pigments, relative water content (RWC), lipid peroxidation, photosynthesis, photosystem II efficiency, and changes in activity of various antioxidative enzymes were studied in the halophyte Salvadora persica treated with various levels of salinity (0, 250, 500, 750, and 1000 mM NaCl) to obtain an insight into the salt tolerance ability of t...

BACKGROUND Chronic heart failure (CHF) results in limb and respiratory muscle weakness, which contributes to exercise intolerance and increased morbidity and mortality, yet the molecular mechanisms remain poorly understood. Therefore, we aimed to compare parameters of antioxidative capacity, energy metabolism, and catabolic/anabolic balance in diaphragm and quadriceps muscle in an animal model ...

Oxygen, while being an obligate fuel for aerobic life, has been shown to be toxic through its deleterious reactive species, which can cause oxidative stress and lead ultimately to cell and organism death. In marine organisms, reactive oxygen species (ROS), such as the superoxide anion and hydrogen peroxide, are generated within respiring cells and tissues and also by photochemical processes in ...

In the present work it is demonstrated that Salicylic acid (SA) and Methyl Jasmonate (MeJA) provided protection of photosynthesis (A) against paraquat (Pq) stress and diminished the oxidative damage caused by Pq. Barley seedlings (12d old) were supplied with 500 μM SA, 23 μM MeJA or 10 μM Pq via the transpiration stream and kept in the dark for 24 h. They were then exposed to 100 μmol.m–2.s–1 P...

Cigarette smoking causes many chronic diseases but is a preventable risk factor in developing countries. However, it may be possible to relieve the smoke-induced damage by increasing the protective defense system. As vitamin C intake reduces smoking risk, it is recommended that smokers should take more vitamin C. However, the molecular mechanism of vitamin C intake on smokers has not been thoro...

Abstract: Background: Ajos sacha is a shrubby herb and has attracted scientists’ attention due to its antioxidative, antineoplastic, larvicidal, antibacterial properties. Hence, assessed in vitro vivo diabetes protective Materials Methods: The methodology started with the quantitative phytochemical estimation of ethanolic extract Adenocalymma alliaceum (EEAA). Then, was studied for cytotoxicity...