A highly bioactive bone-bonding Ti metal was obtained when Ti metal was simply heat-treated after a common acid treatment. This bone-bonding property was ascribed to the formation of apatite on the Ti metal in a body environment. The formation of apatite on the Ti metal was induced neither by its surface roughness nor by the rutile phase precipitated on its surface, but by its positively charge...

IN OSTEOBLAST TRANSPLANTATION +*Maeno, S; *Niki, Y; *Yatabe T; *Funayama A; *Matsumoto H; *Toyama Y; **Taguchi, T; **Tanaka J +*Keio University, Tokyo, Japan **Biomaterial Center, National Institute for Material Science, Ibaraki, Japan Introduction Recently, many efforts have been undertaken to repair articular cartilage lesions by transplantation of autologous chondrocytes cultured and expande...

Biomedical titanium metals subjected to gas under precisely regulated oxygen partial pressures (PO2) from 10 to 10 Pa at 973 K for 1 hour were soaked in a simulated body fluid (SBF), whose ion concentrations were nearly equal to those of human blood plasma, at 36.5 C for up to 7 days. After soaking in SBF, the following relationship held: The growth rate of apatite decreased in the order PO2 of...

Bioactive glasses were synthesized in an inexpensive hydrothermal chemical route by the use of microwave energy irradiation. Compositional changes were carried out to synthesis bioactive glass with different Si content. Densification behavior was investigated by microwave sintering process from 700 °C to 1000 °C temperature. The powders were characterized for their physical and morphological ch...

Unraveling the mechanisms behind the processes of cell attachment and the enhanced proliferation that occurs as a response to the presence of calcium silicate-based materials needs to be better understood so as to expand the applications of silicate-based materials. Ions in the environment may influence apatite precipitation and affect silicate ion release from silicate-based materials. Thus, t...

To reveal general principles for obtaining bone-bonding bioactive metallic titanium, Ti metal was heat-treated after exposure to a solution with different pH. The material formed an apatite layer at its surface in simulated body fluid when heat-treated after exposure to a strong acid or alkali solution, because it formed a positively charged titanium oxide and negatively charged sodium titanate...

Poly-L-lactide/β-tricalcium phosphate (PLLA/β-TCP) porous scaffold fabricated by freeze shrinking/particulate leaching was studied. The scaffold was immersed into simulated body fluid (SBF) for 1, 2, 3 and 4 weeks and analyzed by the SEM, XRD and FT-IR spectroscopy. The ability of inducing Ca-P formation was compared among the scaffolds with different content of βTCP. SEM shows a typical featur...

We report on the bioactivity of two series of glasses in the SiO(2)-Na(2)O-CaO-P(2)O(5) system after immersion in simulated body fluid (SBF) after 21 days. The effect of P(2)O(5) content was examined for compositions containing 0-9.25 mol.% phosphate. Both series of glasses degraded to basic pH, but the solutions tended towards to neutrality with increasing phosphate content; a result of the ac...