Erlotinib (ELT) as a small molecule with poor solubility, poor bioavailability, and instability in gastrointestinal environment, has been considered as a therapeutic agent for Non-Small-Cell Lung Cancer (NSCLC) therapy through oral administration. In the present study, ELT-liposome and ELT-NLCs were successfully prepared and characterized by assessment of the particle size, zeta potential (ZP),...

In this paper a new implementation of the two-dimensional Extended Lapped Transform (2-D ELT) is proposed. Compared to the separable solution, proposed by Malvar [1], the new realization of 2-D ELT has reduced arithmetic complexity. Computational savings are achieved because scaling and inverse scaling of butter y matrices, suggested by Malvar for 1-D case, are, after some modi cations of the b...

The paper tries to answer the question--to what extent the English Language Teaching theory informs the ELT practice in a reflective case study. It argues that even if it is challenging considering what is beyond the theory in practical use of theory, yet if teacher educators in the field of ELT have a solid academic foundation, they will have the responsibility and capacity to challenge the th...

The identification and prioritization of chemically tractable therapeutic targets is a significant challenge in the discovery of new medicines. We have developed a novel method that rapidly screens multiple proteins in parallel using DNA-encoded library technology (ELT). Initial efforts were focused on the efficient discovery of antibacterial leads against 119 targets from Acinetobacter baumann...

BACKGROUND Diagnostic test panels have been advocated by the Japan Society of Clinical Pathology for evaluation of presenting complaints of new outpatients in primary care medicine. The tests have additional potential utility for opportunistic finding of asymptomatic diseases, but data are lacking on the number of new conditions identified by the test panels and on the cost per identified case....

This paper develops a new approach to the detection of the emergency locator transmitter (ELT) signal using an adaptive line enhancer (ALE). The input signal to the ALE is replaced by its autocorrelation function (ACF) because noise affects the central samples of the autocorrelation function only while it affects all samples of the noisy signal. This gives the ALE the ability to get rid of nois...

In the past decade, Caenorhabditis elegans has been used to dissect several genetic pathways involved in immunity; however, little is known about transcription factors that regulate the expression of immune effectors. C. elegans does not appear to have a functional homolog of the key immune transcription factor NF-kappaB. Here we show that that the intestinal GATA transcription factor ELT-2 is ...

BACKGROUND The influence of embryo loading time (ELT) and the time interval between embryo loading and embryo transfer (TIEL-ET) on the success of IVF/ICSI is unknown. METHODS In a prospective cohort study, we aimed to ascertain the influence of ELT and TIEL-ET on ongoing pregnancy rate (OPR) and life birth rate (LBR). Data from 603 consecutive embryo transfers between January 2008 and Decemb...

introduction the purpose of this study was to evaluate personal shields in radiation departments of hospitals affiliated to mashhad university of medical sciences. materials and methods first, the information related to 109 personal shields was recorded and evaluated by imaging equipment. afterwards, the equivalent lead thickness (elt) of 62 personal shields was assessed, using dosimeter and st...

In this paper we have studied the combination of Elzaki and Laplace transforms to produce a degenerative new double integral transform, transform called Elzaki-Laplace (ELT), then applied it some partial differential equations find its exact solution.