PURPOSE To report a retrospective series of seven phakic eyes of seven patients suffering from a malignant glaucoma-like syndrome following pars plana vitrectomy and silicone oil (SO) injection. MATERIALS AND METHODS Seven eyes with retinal detachment treated with pars plana vitrectomy with or without scleral buckling with SO tamponade. This was followed by cataract extraction to manage the e...

PURPOSE To determine whether the capacity to induce ACAID by antigen injection into the anterior chamber is altered in animals with genetically determined retinal degeneration and increased age. METHODS Anterior chamber-associated immune deviation (ACAID) induced by injection of ovalbumin into the anterior chamber of the eye was studied in three rodent strains with different forms of heredita...

Delivery of 2.1 microgram of cholera toxin, a specific, irreversible activator of adenylate cyclase, via the blood lowers IOP from 17.4 to 11.2 mm Hg in 81/2 hr. decreases net aqueous flow by about 50% in 8 hr, and doubles blood flow to the anterior uvea at 8 to 13 hr. Intravitreal injection of 0.26 microgram of cholera toxin lowered IOP from 15.0 to 9.6 mm Hg, but heat-inactivated toxin had no...

Substantial levels of acyclovir were detected in the aqueous and vitreous of New Zealand rabbits at various time intervals following subconjunctival injection. Intravitreal penetration of acyclovir after topical application was poor.

Ouabain was injected into the vitreous humor of one eye of rabbits in doses of 0.1, 0.2 and 0.5 meg. Aqueous humor inflow in the injected eye was inhibited significantly 49, 51, and 78 per cent, respectively, in these three dose groups 4 to 5 days after injection. In vitro Na-K activated ATPase activity of the ciliary body was inhibited significantly by 24, 16, and 27 per cent, corresponding to...

regarding the effects of coriandrum sativum (C. sativum) on central nervous system, in the present study analgesic properties of different extracts of C. sativum aerial parts were investigated. the mice were treated by saline, morphine, three doses (20, 100 and 500 mg/kg) of aqueous, ethanolic, choloroformic extracts of C. sativum and one dose (100 mg/kg) of aqueous, two doses of ethanolic (100...

The medicinal plant Olea europaea L. is a valuable one whose fruit and its oil are considered as food. There are some reports in ancient medical literature that aqueous extract of its leaves has analgesic effects. This prompted us to investigate the analgesic effect of aqueous extract of its leaves using formalin and tail-flick tests. For this purpose, male NMRI rats weighting 220-260 g were us...

PURPOSE To assess aqueous humor dynamics in mouse eyes. METHODS Aqueous humor dynamics of NIH Swiss White mouse were assessed with an injection and aspiration system, using fine glass microneedles. Intraocular pressure (IOP) was measured by a microneedle connected to a pressure transducer. Episcleral venous pressure (EVP) was measured by gradually lowering intracameral pressure until blood re...