نتایج جستجو برای: arrhythmogenicity

تعداد نتایج: 246  

Journal: :Canadian Anaesthetists' Society journal 1984
C C Rao S F Dierdorf T M Wolfe K A Haselby G Krishna R R Paradise

The effect of age on the arrhythmogenicity of epinephrine during halothane anaesthesia was studied in pigs of two different age groups. At a stable alveolar concentration of 0.84 volumes per cent halothane, ventricular arrhythmias could not be elicited in one- to three-day-old pigs by a 100 micrograms X kg-1 infusion of epinephrine. PVCs were produced in 50- to 55-day-old pigs at a mean epineph...

Journal: :Biophysical journal 2009
Rebecca C Ahrens-Nicklas David J Christini

Interspecies differences can limit the translational value of excitable cells isolated from model organisms. It can be difficult to extrapolate from a drug- or mutation-induced phenotype in mice to human pathophysiology because mouse and human cardiac electrodynamics differ greatly. We present a hybrid computational-experimental technique, the cell-type transforming clamp, which is designed to ...

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