Background: Patients with cirrhosis often develop hypoalbuminemia. In conditions of hepatic dysfunction, albumin synthesis is decreased due to dysfunction and abnormal distribution portal blood flow. Ascites a major complication an important sign in the course associated 50% mortality after two years. 75% patients' ascites etiology liver cirrhosis, 10% malignancy, 3% heart failure, 2% tuberculo...

PURPOSE Vascular endothelial growth factor (VEGF) levels in malignant ascites have high diagnostic value for their discrimination from ascites of non-malignant origin. However, there have been no reports on the comparison of VEGF levels between malignant ascites of chemonaive and chemotreated patients. MATERIALS AND METHODS VEGF levels were measured in 44 ascites patients (cirrhosis ascites, ...

background: ascitic fluid infection is presumptively diagnosed when the fluid polymorph nuclear (pmn) concentration equals or exceeds 250 cells /mic,l. the leukocyte esterase (le) test has been shown to be a good predictor of the presence of pmns in urine and other body fluids. this study examines of value of multistix 8sg dipstick test for rapid diagnosis of infected ascitic fluid. materials a...

the objective of this study was to assess the importance of strain and sex and their interaction effect on broiler chickens’ performance and susceptibility to ascites. chicks from three strains (ross 308, cobb 500 and arian, labeled as a, b and c respectively) were obtained from the same age breeder and sexed when one-day-old. each crosses’ sex was assigned to four pens of 60 broilers each. bod...

Chemotherapy resistance is the major reason for the failure of ovarian cancer treatment. One mechanism behind chemo-resistance involves the upregulation of multidrug resistance (MDR) genes (ABC transporters) that effectively transport (efflux) drugs out of the tumor cells. As a common symptom in stage III/IV ovarian cancer patients, ascites is associated with cancer progression. However, whethe...

BACKGROUND In gastric cancer, poor prognosis is associated with peritoneal dissemination, which often accompanies malignant ascites. We searched for a target molecule in peritoneal metastasis and investigated its clinical utility as a biomarker. METHODS Biopsy specimens from both primary lesions and peritoneal metastasis, and if possible, malignant ascites, were obtained from 40 patients with...

Purpose: Ovarian cancer patients with malignant ascites have poor prognosis. The accumulation of ascites is caused by an imbalance between fluid extravasation from the blood vessels and reabsorption by lymphatic vessels. Whereas, the role of TGF-b in tumor progression has been well studied, the role of TGF-b in lymphatic vessel function is far from understood. Here, we sought to dissect the rol...

INTRODUCTION Spontaneous bacterial peritonitis (SBP) as a monomicrobial infection of ascites fluid is one of the most important causes of morbidity and mortality in cirrhotic patients. This study was aimed to determine the diagnostic accuracy of ascites fluid color in detection of SBP in cirrhotic cases referred to the emergency department. METHODS Cirrhotic patients referred to the ED for th...

Epithelial ovarian cancer consists of multiple histotypes differing in etiology and clinical course. The most prevalent histotype is high-grade serous ovarian cancer (HGSOC), which often presents at an advanced stage frequently accompanied with high-volume ascites. While some studies suggest that ascites is associated with poor clinical outcome, most reports have not differentiated between hist...

PURPOSE The aim of this study was to investigate the clinicopathologic features and prognosis in patients with computed tomography (CT) findings of ascites, with a focus on the correlation with peritoneal carcinomatosis. METHODS This study included a total of 157 patients who underwent surgery for advanced gastric cancer from 2003 to 2008 at the Department of Surgery, Hallym University Kangdo...