Asthma is a chronic inflammatory disorder of the airway and is characterized by airway remodeling, hyperresponsiveness, and shortness of breath. Modified Kushen Gancao Formula (mKG), derived from traditional Chinese herbal medicines (TCM), has been demonstrated to have good therapeutic effects on experimental allergic asthma. However, its anti-asthma mechanism remains currently unknown. In the ...

OBJECTIVE To describe beliefs about asthma and asthma treatment in a Hispanic (Dominican-American) community to determine how alternative belief systems affect compliance with medical regimens. METHOD Twenty-five mothers of children with asthma were interviewed in their homes, in their primary language, Spanish. Mothers were questioned about their beliefs regarding asthma etiology, treatment,...

BACKGROUND Asthma is a disease resulting from a complex interaction of multiple genetic and environmental factors. More than 200 asthma candidate genes have been identified in the past decades by using genetic association studies, positional cloning and knockout mouse approaches. AIM This study was to identify differentially expressed genes and provide direction for medicine design related to...

BACKGROUND There is evidence that both personality traits and personal beliefs about medications affect adherence behavior. However, limited research exists on how personality and beliefs about asthma medication interact in influencing adherence behavior in people with asthma. To extend our knowledge in this area of adherence research, we aimed to determine the mediating effects of beliefs abou...

Asthma is a chronic disease with both inflammatory and bronchoconstrictive elements and often requires multiple medications. Most asthma regimens include medications with different therapeutic modes of action and a number of different medication delivery devices. To effectively participate in their asthma management, patients need to recognize each of their medication types, understand their pu...

OBJECTIVE We conducted a national, population-based survey to examine the asthma-related health burden of US children. METHODS A telephone-based survey was conducted in 2004 of children 4 to 18 years of age with current asthma in the United States. In 41,433 households screened, 1089 children reported current asthma; 801 interviews were completed by parents of children aged 4 to 15 years and ...

medicines constitute a substantial proportion of out-of-pocket (oop) expenses in indian households. in order to address this issue, the government of india launched the jan aushadhi (medicine for the masses) scheme (jas) to provide cheap generic medicines to the patients (http://janaushadhi.gov.in/about_jan_aushadhi.html). these medicines are provided through the jan aushadhi stores established...

The general public knows little about herbal medicines, but the popularity and sales of these products have soared with sales totaling $655 mil in 1994, which is expected to reach $1.6 bil by 2001. The use of these herbal remedies in the general public is about 3%, but among patients suffering from AIDS, cancer, arthritis, asthma, and other debilitating conditions, the prevalence of these over-...

Omalizumab (anti-IgE ab) is a recombinant humanized monoclonal antibody (rhuMAb-E25) developed by immunizing mice with human IgE. Then, a monoclonal antibody was selected that recognizes IgE at the same site as the highaffinity receptor for IgE (FcεRI). Omalizumab is the only Mab to date that has been found to be effective and approved by both the FDA and European Medicines Agency (EMA) for the...