OBJECTIVE To observe the effect of high-dose Astragalus injection and cyclophosphamide (CTX) on infection, urine protein and immune function of the patients with lupus nephritis. METHODS Forty-three patients diagnosed as systemic lupus erythematosus (SLE) complicated by kidney damage and qi-deficiency syndrome were randomly divided into trial group (n=23) and control group (n=20). Patients in...

PURPOSE Systemic treatments for advanced non-small-cell lung cancer have low efficacy and high toxicity. Some Chinese herbal medicines have been reported to increase chemotherapy efficacy and reduce toxicity. In particular, Astragalus has been shown to have immunologic benefits by stimulating macrophage and natural killer cell activity and inhibiting T-helper cell type 2 cytokines. Many publish...

the taxonomic and phylogenetic status of several taxa previously recognized as subspecies inastragalus sect. anthylloidei is re-assessed based on dna sequences and morphologicalfeatures. we focused on astragalus ebenoides (subsp. ebenoides and subsp. naghadehensis),astragalus murinus (subsp. murins and subsp. bornmuelleri), astragalus remotiflorus (subsp.remotiflorus and subsp. melanogramma), a...

BACKGROUND Chinese herbal injections (CHIs) have been proven beneficial to patients with gastric cancer for improving clinical efficacy and relieving adverse reactions (ADRs) of chemotherapy. A network meta-analysis (NMA) was conducted in this study to assess the comparative efficacy and safety of CHIs combined with FOLFOX regimen for treating gastric cancer. RESULTS A total of 2316 records w...

OBJECTIVE To evaluate the antioxidant activities of different chemical constituents from Astragalus mongholicus Bunge and their protection against xanthine (XA)/xanthine oxidase (XO)-induced toxicity in PC12 cells. METHODS The compounds of Astragalus mongholicus Bunge were isolated by chromatography and the structures were elucidated on the basis of spectral data interpretation. Their antioxi...

Astragalus roots from Astragalus membranaceus Bunge or Astragalus membranaceus var. mongholicus (Bunge) Hsiao are among the most popular traditional medicinal plants due to their diverse therapeutic uses based on their tonic, antinephritic, immunostimulant, hepatoprotectant, diuretic, antidiabetic, analgesic, expectorant and sedative properties. Currently, the herb is produced or cultivated in ...

Phylogenetic analyses of large data sets pose special challenges, including the apparent tendency for the bootstrap support for a clade to decline with increased taxon sampling of that clade. We document this decline in data sets with increasing numbers of taxa in Astragalus, the most species-rich angiosperm genus. Support for one subclade, Neo-Astragalus, declined monotonically with increased ...

melanin pigment plays a critical role in camouflage and   protection against harmful effects of solar radiation. melanogenesis is under   complex regulatory control by multiple agents. tyrosinase is a   multifunctional, which catalyzes the first two steps in mammalian   melanogenesis. in this study, inhibitory effects of astragalus fasciculifolius   and astragalus gypsicolus on diphenolase acti...