D ecreased availability of nitric oxide (NO), which contributes to the development of diabetes vascular complications (1), is partially related to asymmetric dimethylarginine (ADMA). ADMA is an endogenous NO synthase inhibitor (2) and a competitive inhibitor of cellular L-arginine uptake (3). ADMA has been associated with atherosclerosis in nondiabetic populations (4) and with diabetic nephropa...
