BACKGROUND Several risk factors for the development of asthma and atopic disease in children have been described. Furthermore, there is consistent evidence that the prevalence of atopy increases with higher socioeconomic status. The knowledge about risk factors and preventive factors for atopy needs to be improved. OBJECTIVE To compare 2 child populations (foster care and reference children) ...

BACKGROUND Atopic dermatitis (AD) is a public health problem, with an increasing prevalence worldwide. AD is a chronic inflammatory disease characterised by skin lesions and severe itching. Immunologically, AD has two forms, IgE-mediated and cell-mediated, but it may also be idiopathic. In the pathogenesis of AD, the gene mutations for filaggrin, a filament-aggregating protein present in the ep...

BACKGROUND Asthma prevalence is increasing worldwide in most populations, likely due to a combination of heritable factors and environmental changes. Curiously, however, some European farming populations are protected from asthma, which has been attributed to their traditional lifestyles and farming practices. OBJECTIVE We conducted population-based studies of asthma and atopy in the Hutterit...

Background and objective: The most supported theory for Nephrotic Syndrome (NS) etiology is that it immune-mediated. This study aims to assess the level of serum IgE in children with Steroid Sensitive NS (SSNS) at relapse remission, its correlation presence atopy. Methods: cross-sectional was approved by Department Pediatrics, College Medicine, Al-Nahrain University (Baghdad, Iraq) conducted Al...

Background Atopy in children with recurrent wheeze is the best predictor for persistent asthma. A high prevalence of atopy was found in children with recurrent wheeze who were at high risk of developing persistent asthma based on the Asthma Predictive Index (API)[1]. A newly modified API now includes allergic sensitization to aeroallergens and to foods as criteria for the risk assessment of per...

Asthma is the most common chronic childhood disease worldwide and poses a significant health and socioeconomic burden. The prevalence of this disease differs geographically and seems on the rise in many parts of the world. (1). Cross-sectional and longitudinal studies have identified several indicators associated with high risk of asthma (2). Personal history of atopy in early life seems to be ...