Introduction: Along with advances occurring in cardiopulmonary bypass (CPB) including improved anesthesia intubation and early surgical interventions, it has become possible to correct life-threatening congenital heart anatomic abnormalities in patients. Our study aimed to collect information from one of the most important centers of pediatric cardiac surgery in Iran since there is limited info...

Four-fifths of the infants with transposition of the great vessels die within the first year of life (Abbott, 1936). Fifty-two per cent. die within the first month and 86% are dead within six months (Keith, Neill, Viad, Rowe, and Chute, 1953). This lesion in some form occurs in 20% of necropsies on patients with congenital heart disease (Keith, Rowe, and Vlad, 1958). In Birmingham, transpositio...

A50-year-old man was accepted as a multiorgan donor. The cause of death was cranioencephalic trauma. No pathological antecedents were found. Transthoracic echocardiography showed neither valvular nor contractility abnormalities. Cardiectomy was performed as usual. A traumatic interatrial septal defect was found in the donor heart preparation before transplantation (Figure 1). It did not involve...

atrial septal defect (asd) is a common congenital anomaly that has low surgical mortality and morbidity. we report a very rare case of a low-lying asd, combined with the drainage of the inferior vena cava and the left superior vena cava into the left atrium. this combination was associated with an unroofed coronary sinus. we also describe an iatrogenic surgical diversion of the inferior vena ca...

Isolated secundum atrial septal defect is one of the most common congenital heart defects. Surgical closure is the treatment of choice but is associated with a chest scar, some morbidity and a relatively long recovery and the use of cardiopulmonary bypass. Transcatheter closure of secundum atrial septal defect is therefore an attractive approach. 3 children, aged 5-10 years, underwent successfu...

The aim of the present study was to determine if patients with both pulmonary arterial hypertension (PAH), due to pulmonary vascular obstructive disease, and congenital heart defects (CHD), have mutations in the gene encoding bone morphogenetic protein receptor (BMPR)-2. The BMPR2 gene was screened in two cohorts: 40 adults and 66 children with PAH/CHD. CHDs were patent ductus arteriosus, atria...

BACKGROUND Children with Down syndrome (DS) have about a 40 to 50% incidence of congenital heart disease (CHD). The objectives of this study were to evaluate the distribution and frequency of CHD patterns in Libyan children with DS. METHODS All patients with DS who were referred to the cardiology clinic between January 1995 and December 2008 were reviewed. RESULTS Of the 1 193 patients revi...

OBJECTIVE To examine the incidence of raised pulmonary artery pressure and resistance in adults with isolated atrial septal defect within the oval fossa (so called secundum defect) or sinus venosus defect. DESIGN A historical, retrospective, unrandomised study. SETTING A tertiary referral centre. METHODS Cardiac catheterisation was performed in all patients, with measurement of pulmonary ...

UNLABELLED An infant, showing peripheral cyanosis, was born after lower abdominal peripheral caesarian section of the pregnant women having TORCH positive test with the infection of Toxoplasma gondiiand Cytomegalovirus. She had three abortions prior to this pregnancy. Doppler echocardiography of the baby showed profound intracardiac defects. After birth, echocardiography was carried out for dia...

49,xxxxy is rare chromosomal pattern and these patients have mental retardation, small penis, cryptorchidism and skeletal anomalies. we reported a 10 month-old boy who has hypotonia, microcephaly, hypertelorism, depressed nasal bridge, epicanthic folds and bilateral multiple ear tags, high arched palate, down set ears, micrognathia and congenital heart disease such as patent ductus arteriosus (...