BACKGROUND Autism is a syndrome of unknown cause, marked by abnormal development of social behavior. Attempts to link pathological features of the amygdala, which plays a key role in emotional processing, to autism have shown little consensus. OBJECTIVE To evaluate amygdala volume in individuals with autism spectrum disorders and its relationship to laboratory measures of social behavior to e...

Autism is a severe neurodevelopmental disorder that characterized by abnormal bilateral social interaction, deficiency in verbal and nonverbal communication, restricted interests and repetitive behaviors .autism caused by the inappropriate immune response which released several cytokines. One of the most important and main causes of autism is a defect in, the formation of the neuronal synaptic ...

BACKGROUND The inheritance pattern in most cases of autism is complex. The risk of autism is increased in siblings of children with autism and previous studies have indicated that the level of risk can be further identified by the accumulation of multiple susceptibility single nucleotide polymorphisms (SNPs) allowing for the identification of a higher-risk subgroup among siblings. As a result o...

Background: This research aimed to estimate the effect of instructional multimedia on communicational skills learning of autism students at 3rd grade elementary school in Tehran. Methods: The method of this research was quasi- experimental and population was all the autism students at 3rd grade elementary school in Tehran.16 students were chosen by accessible sampling and they were randomly div...

how to cite this article: mohammadi mr, salmanian m, akhondzadeh sh. autism spectrum disorders in iran. iranian journal of child neurology2011;5(4):1-9. objective autistic disorder, asperger syndrome, and pdd-not otherwise specified are subsets of autism spectrum disorders (asds), which are characterized by impairments in social communication and stereotyped behavior. this article reviews the p...

BACKGROUND Methyl-CpG-binding protein-2 (MeCP2) is a critical regulator for neural development. Either loss- or gain-of-function leads to severe neurodevelopmental disorders, such as Rett syndrome (RTT) and autism spectrum disorder (ASD). We set out to screen for MECP2 mutations in patients of ASD and determine whether these autism-related mutations may compromise the proper function of MeCP2. ...

introduction: pulmonary involvement secondary to systemic sclerosis (ssc) is the major cause of morbidity and mortality in ssc patients. we designed this study to determine the correlation of important lung function parameters with lung high resolution ct (hrct) scan findings.materials and methods: thirty–two consecutive diffuse ssc patients with pulmonary fibrosis were enrolled in this cross-s...

The hyper-systemizing theory of autism proposes that the systemizing mechanism is set too high in people with autism. As a result, they can only cope with highly lawful systems, and cannot cope with systems of high variance or change (such as the social world of other minds). They appear 'change-resistant'. This proposal extends the extreme male brain theory of autism. Finally, evidence is revi...

BACKGROUND Autism is a complex disorder characterized by deficits involving communication, social interaction, and repetitive and restrictive patterns of behavior. Twin studies have shown that autism is strongly heritable, suggesting a strong genetic component. In other disease states with a complex etiology, such as type 2 diabetes, cancer and cardiovascular disease, combined analysis of multi...

In this article, we will describe a big summary (called meta-analysis) of 16 brain mapping studies in people with autism spectrum disorder. People often have difficulty activities like decision-making, planning, and switching between tasks, which are called executive function (EF) activities. We found that certain parts the become more activated when EF being performed. autism, these regions do...