نتایج جستجو برای: autoimmune lymphoproliferative syndrome

تعداد نتایج: 678796  

2014
Beatriz Wills Sanín Yenny R. Cárdenas Bolivar Jose J. Carvajal Guillermo E. Quintero Rafael Andrade

Introduction. The clinical course of an autoimmune paraneoplastic syndrome parallels the natural history of the primary malignancy. In most cases, such paraneoplastic are syndromes hardly distinguishable from idiopathic autoimmune diseases. A case of polyangiitis with granulomatosis as a paraneoplastic syndrome in a patient with B-cell Lymphoma of the lacrimal gland has not yet been reported. C...

Journal: :British journal of haematology 2009
David T Teachey Robert Greiner Alix Seif Edward Attiyeh Jack Bleesing John Choi Catherine Manno Eric Rappaport Dirk Schwabe Cecilia Sheen Kathleen E Sullivan Hongming Zhuang Daniel S Wechsler Stephan A Grupp

We hypothesized that sirolimus, an mTOR inhibitor, may be effective in patients with autoimmune lymphoproliferative syndrome (ALPS) and treated patients who were intolerant to or failed other therapies. Four patients were treated for autoimmune cytopenias; all had a rapid complete or near complete response. Two patients were treated for autoimmune arthritis and colitis, demonstrating marked imp...

Journal: :Iranian journal of allergy, asthma, and immunology 2010
Hamid Reza Kianifar Maryam Khalesi Reza Farid Zahra Badiee Maryam Rastin Hamid Ahanchian

Autoimmune lymphoproliferative syndrome (ALPS) is an uncommon nonmalignant lymphoproliferative disease which is characterized by chronic, persistent or recurrent lymphadenopathy, splenomegaly, hepatomegaly, immune cytopenia , hypergammaglobinemia and increased risk of lymphoma. We report a 2-year old boy with hepatosplenomegaly as first presentation. Petechial and purpuric rashes with massive c...

Journal: :Iranian journal of allergy, asthma, and immunology 2004
Toshio Miyawaki

Epstein-Barr virus (EBV) is a ubiquitous human gamma-herpesvirus that infects about 95% of the adult population. The majority of primary infections occurs in early childhood and is generally subclinical; it can cause infectious mononucleosis (IM), which is usually a self-limiting lymphoproliferative disorder. However, infection of EBV occasionally results in severe, often lethal diseases, which...

Journal: :Annals of oncology : official journal of the European Society for Medical Oncology 2007
T R Mikuls

editorial The treatment of lymphoma complicating autoimmune disease: two birds with one stone? Lymphoproliferative diseases, particularly non-Hodgkin's lymphoma (NHL), have increased dramatically in frequency during the last three decades with a more than twofold increase in NHL incidence from the mid-1970s to the mid-1990s alone. NHL is currently the fifth most common malignancy in the USA wit...

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